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Please select the option that best describes you:
Topics:
Rheumatology
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Antiphospholipid Syndrome
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Systemic lupus erythematosus
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Benign Hematology
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Anticoagulation
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Hospital Medicine
How would you approach a patient with SLE and catastrophic antiphospholipid antibody system that has not responded to heparin, steroids, and PLEX?
How do you decide amongst other therapies such as eculizumab, rituximab, cyclophosphamide, IVIg?
Related Questions
How would you work up splenomegaly and abdominal pain in a patient with primary antiphospholipid syndrome and a high + ANA, but no other serological or clinical SLE symptoms?
How do you manage patients with positive antiphospholipid antibodies in the perioperative setting for solid organ transplant, such as renal transplant?
In patients with lupus nephritis, and MAHA with positive anti-phospholipid autoantibodies, what are the considerations to use or not use anti-coagulation therapy?
How often should lupus anticoagulant be checked in patients with SLE if prior was negative or if prior was positive?
Can anti-cardiolipin or anti-beta-2 glycoprotein antibodies cause prolonged PTT in the absence of a lupus anticoagulant?
Do you hospitalize patients with newly diagnosed lupus nephritis and nephrotic syndrome if you are able to provide pulse steroids outpatient and follow them closely?
For patients with SLE, is there an ANC level for which you would hold or adjust hydroxychloroquine in an asymptomatic patient?
Is there any role for IVIG or steroids in viral myositis complicated by severe rhabdomyolysis, diffuse compartment syndrome, DIC, and AKI?
Would you start anticoagulation in a previously heathy patient with a new diagnosis of ANCA vasculitis (+PR3, RPGN, crescents on kidney biopsy) who presented with pancreatitis, splenic and renal infarcts and was also found to have CMV viremia?
What is your preferred add-on for membranous lupus nephritis (2.2 grams of protein, normal creatinine) in a young woman who is currently on hydroxychloroquine and mycophenolate 1500 mg 2x daily?