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In the setting of platinum resistant ovarian cancer, do you consider repeat use of bevacizumab with subsequent lines of chemotherapy following prior treatment with chemotherapy + bevacizumab with bevacizumab maintenance?

Considering the treatment of platinum resistant ovarian cancer as done in the AURELIA trial (Pujade-Lauraine et al., PMID 24637997).
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How do you use bevacizumab in the treatment of platinum resistant ovarian cancer?

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Gynecologic Oncology · Cooper Medical School of Rowan University
Answered on

I typically do reuse bevacizumab. Now that bevacizumab is approved for front-line, maintenance, and recurrent settings, many patients with recurrence may not be bev-naive, to begin with, and I still use bev+chemo.

In breast cancer (von Minckwitz et al., PMID 25273342) and colon cancer (Bennouna et al...

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