In what situations would you consider focal irradiation for nodular leptomeningeal disease?
1 Answer
Mednet MemberInvited Expert
Radiation Oncology · Columbia University Irving Medical Center
Answered on · Updated on
So in general, for patients with LMD, I would recommend WBRT - if RT were indicated. A recent paper in the red journal (Turner et al., PMID 31605786) separated "classical LMD" versus "nodular LMD" and provided a training module to improve interrater reliability. In my practice, even patients who present with nLMD I would still discuss WBRT as a standard therapy, and maybe for select cases, would I consider focal RT. The cons to focal RT is in the event where a patient progresses with out of fiel...
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