What is your approach to chemoprevention for HR+ DCIS in the ipsilateral breast in a patient who already completed 7 years of an AI for a prior HR+ invasive breast cancer?
2 Answers
Mednet MemberInvited Expert
Medical Oncology · University of Utah Huntsman Cancer Institute
Answered on
This is a not-uncommon scenario. What is the appropriate use of endocrine therapy after ipsilateral breast tumor recurrence or second primary breast cancer in a patient who has recently completed hormonal therapy?
As shown in the Breast Cancer Prevention Trial (P-1), MAP.3, and IBIS II, both SERMs an...
Join for free or sign in to see the full answer
Mednet Member
Medical Oncology · Medical College of Wisconsin
Answered on
In this case, chemo prevention is obviously for the contralateral breast. I agree with Dr. @Dr. First Last in considering an AI or tamoxifen if prior ET was more than 5 years ago. What is the use of switching to another AI or tamoxifen for chemo prevention while they are already on ET for invasive d...
Join for free or sign in to see the full answer