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Would you offer PA nodal XRT in a patient with rising PSA and multiple PET positive nodes after previous prostate XRT treatment that is otherwise locally controlled?

For instance, if the fluclicovine scan shows a few small avid nodes not only in the pelvis but extending to the paraaortic region, would you treat these or just put the patient on ADT? How high would you extend your para-aortic field?
2 Answers
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Radiation Oncology · Harvard Medical School
Answered on

This is a great question, and one that is being explored more and more, particularly for young, healthy patients with well-controlled primary disease. In addition, we are seeing more of these patients due to novel developments in imaging that can detect disease at much lower PSA values than before (...

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Radiation Oncology · Varian Medical Systems/Allegheny health network
Answered on

https://www.ncbi.nlm.nih.gov/pubmed/31331782

The above study with the obvious limitation of retrospective analysis, suggests better regional nodal control with elective RT vs SABR for isolated nodal relapse detected on advance PET imaging and also better MFS in pts with single nodal disease.

Elective...

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