Would you treat pelvic lymph nodes in your salvage prostate patient after RP without adverse features due to a limited/no pelvic lymph node sampling?

No, not based on lack of extended PLND, alone.

RADICALS left lymph node coverage to physician discretion, and only 3% of salvage patients received pelvic lymph node irradiation. 44% of the patients on RADICALS had no lymph node dissection.

Strongest evidence in favor is SPPORT, with biochemical contr...