theMednetRegister

Hepatology

Transplant Hepatology   

Questions discussed in this category

How are you treating MSI-H CRC in a liver transplant recipient on tacrolimus & sirolimus?
History of OLT (3 years ago), no response to pembro mono tx after 2 mo. Too immunosuppressed?
2 Answers available
What is your approach to discussions with patients about the MELD score, its use for prognostication of outcomes and decompensation?
1 Answer available
How do you consider sending fungal studies in a patient with pneumonia?
Considering the recent article in CHEST that describes the increasing incidence of fungal pneumonia Azar. Chest 2024
3 Answers available
Would you refer a patient for kidney only or kidney and liver transplantation if they develop advanced chronic kidney disease secondary to primary hyperoxaluria type 2?
2 Answers available
Under which circumstances is there a role for reduction in immunosuppression post-SOT in a patient with recurrent CMV viremia and/or disease? 
1 Answer available
How long do you treat uncomplicated gram-negative rod bacteremia in solid organ transplant recipients?
1 Answer available
What is your approach to liver transplantation candidacy in those with decompensated cirrhosis who have been treated for a solid-organ malignancy, such as oral SCC?
Is there a minimum time of waiting that is necessary between the completion of cancer treatment and liver transplantation?
1 Answer available
For cirrhotic patients that we take care of in the community, when should be the optimal timing of referral for liver transplantation aside from the MELD score?
Is there such a thing as "too early" referral? How can we best utilize the time and resources of a liver transplant center for such patients?
2 Answers available
What cardiac testing do you perform for patients undergoing liver transplant evaluation?
1 Answer available
For remote liver transplant recipients back under the care of a community gastroenterologist (or PCP), what should be the approach to new liver enzyme elevations?
What should be ordered? Any medications given?
1 Answer available
What graft and patient factors would increase the risk of early graft failure?
What are your management/preventative strategies, and are they specific to your experiences and/or institution?
1 Answer available
Are there any specific guidelines for the transplantation of metastatic disease to the liver or are these institution specific?
In general, for which malignancy would this most commonly be entertained and what patient criteria would make them an optimal candidate?
1 Answer available
Having gone through multiple iterations, what MELD updates/considerations should we anticipate in the future?
1 Answer available
What are your diagnostic and treatment goals for a patient with cirrhotic cardiomyopathy?
Would treating underlying cirrhosis/transplant cure the driver of their cardiac dysfunction, and is this reversible? What unique transplant complicati...
1 Answer available
How do you decide which patient and with which device to pursue machine perfusion for the organ of a liver transplant recipient?
What other patient factors and nuances do you take into consideration in patient selection and use of specific perfusion options (ex: normothermic vs....
2 Answers available
What is your strategy to manage the complication of long-term immunosuppression in liver transplant recipients, specifically renal dysfunction and onset of cardiometabolic comorbidities?
Do you opt for dose reduction? Switching medications?
2 Answers available
What is your strategy to manage peri-procedural bleeding risk in patients with cirrhosis?
Do you use TEG or ROTEM? How do you counsel proceduralists on the unique hemostatic profile of patients with cirrhosis?
1 Answer available
How would you workup a patient who develops ascites AFTER liver transplantation?
2 Answers available
How does the presence of porto-mesenteric vein thrombosis impact a patient's transplant candidacy?
How do you go about working up and managing patients with these findings?
1 Answer available
Is there a serum ammonium level for which you recommend initiation of dialysis in a patient with hepatic encephalopathy?
3 Answers available
Should a patient who requires definitive treatment for prostate cancer as a pre-transplant requirement be strictly required to complete their course prior to transplant/initiation of immunosuppression?
Patient is undergoing RT and has already started on a GnRH antagonist. If so, how long after their last fraction would be an appropriate wait time?
1 Answer available
For how long would you treat a patient with latent TB before allowing them to proceed with a liver transplant?
1 Answer available
With an increase in the prevalence of MASLD in the United States population, what recipient and donor characteristics do you find favorable for acceptance of a highly steatotic graft?
2 Answers available
How do you determine when you would treat an identified spleno-renal shunt and how?
2 Answers available
What would be the right patient profile and experience for someone who may have (operational) tolerance and how do you approach immunosuppresison management (or withdrawal) in this patient?
1 Answer available
Can tacrolimus in a transplant patient be used during radiation and concurrent chemoradiation?
Does your practice differ depending on the disease site?
1 Answer available
How do you determine which patients are good candidates to have their organ receive machine perfusion therapy before implantation?
1 Answer available
What patient features would favor the creation of a Hutson loop intra-operatively?
1 Answer available
How do you approach the evaluation of a living donor liver transplant candidate?
What kind of patient would be an ideal recipient of such an organ?
1 Answer available
How do you counsel patients on the use of marginal organs and/or high risk donors who are on the liver transplant wait list?
1 Answer available
How do you approach risk of development of PTLD in liver transplant recipients with positive EBV antibodies and/or viral loads?
1 Answer available
How much do you factor in a patient's frailty in selection for transplant if the underlying driver for their debility is their underlying liver disease itself?
1 Answer available
How do you approach cognitive impairment in the assessment of transplant candidacy?
1 Answer available
Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?
1 Answer available


Papers discussed in this category

The Journal of infection, 2011-11
Norovirus gastroenteritis successfully treated with nitazoxanide.
Alimentary pharmacology & therapeutics, 2006 Nov 15
Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.
Journal of tropical medicine, 2017 Feb 26
Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020 Oct 23
Pretransplant solid organ malignancy and organ transplant candidacy: A consensus expert opinion statement.
Clinical journal of the American Society of Nephrology : CJASN, 2023 Oct 17
How We Treat Hyperammonemia in Acute Liver Failure.
Cardiovascular and interventional radiology, 2024 Jun 10
Percutaneous Biliary Interventions via the Modified Hutson Loop in Patients with Biliary-Enteric Anastomoses: A Retrospective Study.
Am J Respir Crit Care Med, 2019 Sep 1
Microbiological Laboratory Testing in the Diagnosis of Fungal Infections in Pulmonary and Critical Care Practice. An Official American Thoracic Society Clinical Practice Guideline.
Chest, 2023 Oct 07
A Diagnostic Approach to Fungal Pneumonia: An Infectious Diseases Perspective.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024 Mar 05
Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2024 Update by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM).
Techniques in vascular and interventional radiology, 2016-03
Portal Vein Recanalization and Transjugular Intrahepatic Portosystemic Shunt Creation for Chronic Portal Vein Thrombosis: Technical Considerations.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2022 Jun 16
Cirrhotic cardiomyopathy: Appraisal of the original and revised criteria in predicting posttransplant cardiac outcomes.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2025 Aug 22
AASLD AST Practice Guideline on Adult Liver Transplantation: Diagnosis and management of Graft-Related complications.
Frontiers in oncology, 2025 Oct 29
Navigating the risks: a systematic review of immune checkpoint inhibitor therapy before liver transplant for hepatocellular carcinoma and its impact on allograft rejection and survival outcomes.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2024 Apr 18
Pretransplant use of immune checkpoint inhibitors for hepatocellular carcinoma: A multicenter, retrospective cohort study.
BMC medicine, 2025 Sep 02
Immune checkpoint inhibitors use in liver transplantation for hepatocellular carcinoma: a global cohort study.
European journal of cancer (Oxford, England : 1990), 2021 Mar 12
Transplant rejections associated with immune checkpoint inhibitors: A pharmacovigilance study and systematic literature review.
JAMA oncology, 2025 Oct 01
Outcomes of Solid Organ Transplant Recipients With Advanced Cancers Receiving Immune Checkpoint Inhibitors: A Systematic Review and Individual Participant Data Meta-Analysis.
Nature communications, 2019 Oct 17
Targeting the mTOR pathway uncouples the efficacy and toxicity of PD-1 blockade in renal transplantation.

Related Topics in Hepatology

Copyright © 2026 theMednet
All Rights Reserved.