Medical Oncology

tnbc

Questions discussed in this category

Do you consider post-NAC isolated tumor cells in LNs to be residual disease in TNBC to justify capecitabine?

Would clinical stage or nodal status affect your decision?

Can you safely proceed with breast irradiation during treatment with immunotherapy?

For a node positive, triple negative patient that underwent neoadjuvant chemotherapy followed by breast conservation with a complete pathologic respon...

2 Answers available

What is your preferred adjuvant therapy for a patient with triple negative breast cancer and has a BRCA germline mutation who had minimal to no response to neoadjuvant chemotherapy?

Young patient, germline BRCA carrier with cT1cN0 to ypT2N0 disease after docetaxel/ cyclophosphamide x 4.

2 Answers available

How would you treat an elderly female with residual TNBC following surgery and neoadjuvant Carboplatin and Paclitaxel?

Assume normal cardiac function and no obvious co-morbidities. No anthracycline previously due to age alone. The patient’s BRCA status is unknown...

1 Answer available

How would you approach systemic therapy for a young post-menopausal woman with locoregional TNBC chest wall recurrence treated with definitive radiation?

Patient previously received neoadjuvant ddAC-T with residual disease at surgery, followed by adjuvant capecitabine which was completed 2 months prior ...

1 Answer available

How do you modify TNBC neoadjuvant chemotherapy in patients with multiple sclerosis?

1 Answer available

For a young patient who had a prior pCR to neoadjuvant therapy, would you consider systemic therapy after local resection and radiation of an isolated brain metastatic recurrence of triple negative breast cancer?

CNS recurrence occurred within two years of prior neoadjuvant therapy

1 Answer available

In which scenarios would you consider adjuvant chemotherapy for a patient with T1a N0 triple negative breast cancer?

If so, what would be the regimen that you would consider and what factors would sway you for or against chemotherapy for such patients?

2 Answers available