Neurology

Infectious Disease

Questions discussed in this category

When do you consider repeating CSF studies in a patient with suspected viral encephalitis but overall initially unrevealing CSF?

1 Answer available

When do you consider using a paramedian approach for a lumbar puncture?

1 Answer available

How do you balance the risk of unnecessary treatment with acyclovir against the risk of delaying treatment in encephalitis cases where CSF pleocytosis is absent?

Habis et al., PMID 39096271

1 Answer available

Do you recommend routine neurosyphilis testing in patients being evaluated for dementia?

1 Answer available

What are your vaccine recommendations while patients are on biologics?

2 Answers available

How do you counsel patients and doctors on antibiotic avoidance in myasthenia gravis?

In light of the publication from Uysal et al., PMID 40166923

2 Answers available

What antibiotics would you use for empiric treatment of a brain abscess in patients allergic to penicillin, metronidazole, and vancomycin?

1 Answer available

What are the current treatment options for progressive multifocal leukoencephalopathy in patients without HIV/AIDS?

Are there any clinical trials underway to study additional therapies?

1 Answer available

Do you choose an antibiotic with CSF penetration, such as nafcillin over cefazolin, in the setting of MSSA endocarditis with septic emboli to the brain (assuming no concomitant meningitis or brain abscess)?

3 Answers available

Is history of GBS a contraindication for all future flu vaccines?

2 Answers available

Do you repeat a lumbar puncture in a patient living with HIV diagnosed with and treated for neurosyphilis and if so, when?

1 Answer available

Do you utilize post-vaccination IgG titers to detect common variable immunodeficiency in patients who are about to start or are actively on B cell depleting therapy?

2 Answers available

Does management of NMDA receptor encephalitis change in a patient with HIV/AIDS?

1 Answer available

Do patients on eculizumab or ravulizumab require repeat vaccination against meningococcal infection after a certain interval?

1 Answer available

Do you recommend continuous antibiotic prophylaxis for patients on complement inhibitors such as eculizumab?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

3 Answers available

What is your approach to the treatment of PML-IRIS in patients with HIV who have progressed to AIDS?

1 Answer available

How do you approach the timing of COVID-19 vaccination for patients with multiple sclerosis on B-cell depleting therapies?

3 Answers available

When would you consider checking JC virus prior to initiating biologic therapy?

1 Answer available

Do you treat HIV/AIDS-associated CNS vasculitis with antiretrovirals alone or in combination with steroids?

1 Answer available

Papers discussed in this category

Neurology, 2020 Jul 29

Effect of ocrelizumab on vaccine responses in patients with multiple sclerosis: The VELOCE study.

Cells, 2018 Dec 28

Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients.

Journal of neurovirology, 2018-06

Progressive multifocal leukoencephalopathy in rituximab-treated rheumatic diseases: a rare event.

Clin Microbiol Infect, 2018 Feb 07

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious diseases perspective (Introduction).

Blood, 2020 Jun 18

Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

Journal of translational internal medicine, 2019 Dec 31

Influenza Vaccination and Guillain-Barré Syndrome: Reality or Fear.

The Journal of infectious diseases, 1980 Mar

A study of cephalothin and desacetylcephalothin in cerebrospinal fluid in therapy for experimental pneumococcal meningitis.

Antimicrobial agents and chemotherapy, 1976 Sep

Pharmacological study of cefazolin during intermittent and continuous infusion: a crossover investigation in humans.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2020 May 08

Should we reconsider cefazolin for treating staphylococcal meningitis? A retrospective analysis of cefazolin and cloxacillin cerebrospinal fluid levels in patients treated for staphylococcal meningitis.

Muscle & nerve, 2025 Apr 01

Frequency and Severity of Myasthenia Gravis Exacerbations Associated With the Use of Ciprofloxacin, Levofloxacin, and Azithromycin.

European journal of anaesthesiology, 2019 Oct

Ultrasound-assisted vs. landmark-guided paramedian spinal anaesthesia in the elderly: A randomised controlled trial.

Journal of clinical anesthesia, 2022 Apr 11

Ultrasound-assisted spinal anesthesia: A randomized comparison between midline and paramedian approaches.

Neurology

Infectious Disease

Questions discussed in this category

Papers discussed in this category

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