Pediatric Hematology/Oncology

Aplastic Anemia   

Questions discussed in this category


Treated initially with hATG/CNI/TPO, but then relapsed. Subsequently treated with cyclosporine, danazol, ESA, and alemtuzumab, but still with pancytop...

Would you give a trial of IST first or immediately refer for SCT if the patient has matched siblings?

What would you recommend within the first year after ATG and thereafter if still maintained on cyclosporine?

Such as patients who are frail, elderly, renally impaired? Would you consider sirolimus over cyclosporine or tacrolimus for safer nephrotoxicity prof...


Papers discussed in this category


Blood, 2013 Sep 19

The Lancet. Haematology, 2015-09

Haematologica, 2017-07