Pediatric Oncology

Endocrinology

Questions discussed in this category

How do you monitor risk of erythrocytosis from testosterone use for female to male transgender patients?

1 Answer available

How do you counsel cancer patients when they ask if they should avoid sugar?

9 Answers available

In a young female with severe osteoporosis due to congenital estrogen deficiency, can estrogen be prescribed if genetic testing for congenital disorders reveals a heterozygous Factor V Leiden mutation?

No prior thrombosis; no family history of thrombosis. As per endocrine, the only useful therapy for the osteoporosis is estrogen.

1 Answer available

Are there contraindications to growth hormone therapy in patients who have completed treatment for pediatric cancer?

1 Answer available

When treating patients with immune checkpoint inhibitors, do you routinely check markers of endocrinopathies such as TSH/ACTH, or only when a patient has symptoms?

If so, how often do you check these labs?

1 Answer available

What recommendations do you have for a transgender female patient with history of prothrombin gene mutation who is interested in starting gender affirming hormone therapy?

The patient has no personal history of VTE, but has positive family history of VTE. Any prophylactic anticoagulation options? How would manage...

1 Answer available

How do you incorporate denosumab into the surgical management of giant cell tumor of bone?

Does the degree of resectability affect your management?

2 Answers available

How do you counsel male-to-female transgender patients on the VTE risk of hormonal therapy?

1 Answer available

Papers discussed in this category

BMJ, 2008 May 20

Hormone replacement therapy and risk of venous thromboembolism in postmenopausal women: systematic review and meta-analysis.

Circulation,

Hormone therapy and venous thromboembolism among postmenopausal women: impact of the route of estrogen administration and progestogens: the ESTHER study.

Endocrine reviews, 2019-02-01

Systemic Complications of Acromegaly and the Impact of the Current Treatment Landscape: An Update.

Eur J Endocrinol, 2022 Apr 21

Safety of growth hormone replacement in survivors of cancer and intracranial and pituitary tumours: a consensus statement.

Pediatr Hematol Oncol, 2023 Mar 20

Growth hormone after CNS tumor diagnosis: the fundamentals, fears, facts, and future directions.

Clinics (Sao Paulo, Brazil), 2018 Dec 10

Autophagy and intermittent fasting: the connection for cancer therapy?

Metabolites, 2020 Jul 11

The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH.

Protein & cell, 2014 Jul 12

Regulation of the pentose phosphate pathway in cancer.

Trends in biochemical sciences, 2016 Jan 05

The Warburg Effect: How Does it Benefit Cancer Cells?

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