Sarcoidosis   

Specifically, do you check for any of these: ACE, Vitamin D 1,25, serum lysozyme, soluble IL2 or Adenosine deaminase levels?

Patient with alcoholism referred to rheumatology for elevated ACE level in the setting of new onset mild sensory peripheral neuropathy on nerve conduc...

Do you discontinue HCQ?

If not, are there any serum or CSF tests you consider to be helpful?

Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?

Would you use with DMARDs/biologics or monitor?

Do you use biomarkers or PET scanning to stratify patients who may benefit most from therapy?

Do you obtain serial cardiac PET scans?

Do you typically push for myocardial biopsy in this case? 

Do you treat with only an IV steroid pulse or do you use an oral steroid taper as well? How long of a taper do you typically use?

Lymph node biopsy with non-caseating granulomas and other etiologies (malignancy, infection, vasculitis) ruled out. 

Multiple lesions on PET

Does the type of cardiac involvement impact this choice?