How do you approach patients with pelvic recurrence of prostate cancer after radical prostatectomy?
Is there a preferred duration of ADT? Do you give abiraterone/prednisone or other novel hormone therapy?
If doing radiation, would you just do SBRT to the site of recurrence or a broader field?
Answer from: Medical Oncologist at Academic Institution
Pelvic recurrences after RP are commonly detected due to a rising PSA and identified either with conventional CT/MRI or now more commonly on PSMA PET/CT imaging. The best datasets we have for this not-uncommon clinical situation is the STAMPEDE trial which largely involved newly diagnosed patients w...