How do you define an adequate EBUS when staging NSCLC?
Important question. There is a high degree of variability in the diagnostic performance of EBUS based pretest probability of disease, physician experience and skill, quality control, and evaluation skills of the cytopathologist.
Nice consensus guidelines from CHEST was published a few years back detailing many of the technical aspects that determine quality outcomes - Wahidi et al., PMID 26402427.
EBUS can generally reach stations 2, 4, 7, 10, and 11, however, what is sampled is going to be indiv...
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Agree with the above answer completely. With EBUS, we can sample stations 2, 4, 7, 10, 11, and sometimes even 12. Wanted to add the following practical points to consider.
- If we can see a lymph node on ultrasound, we can sample it. Ideally, we start with N3 lymph nodes and slowly work towards N1, to accurately stage NSCLC.
- Commonly lung nodules are sampled with robotic or navigation bronchoscopy and then pathological staging is done with EBUS.
- On the TBNA sample, the presence of lymphoid tissue...
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I generally refer to CHEST Guideline and Expert Panel Reports to learn more about pulmonology-based procedures: Wahidi et al., PMID 26402427.
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