How do you time re-staging studies and adjuvant durvalumab for stage III NSCLC treated with definitive cCRT?
Do you feel it is important to start durvalumab within 14 days of completing cCRT? What real life challenges do you face in doing so and what have you found to be helpful?
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How often do you start durvalumab within 14 days of completion of radiation for stage III patients receiving definitive chemoradiation?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · Cedars-Sinai Medical Center
Answered on
In the PACIFIC study, 713 patients who received at least 2 cycles of platinum-based chemotherapy with radiation (CRT) and did not develop disease progression were randomly assigned in a 2:1 manner to receive durvalumab at 10 mg/kg every 2 weeks up to 12 months or placebo. Randomization took place be...
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