Stage III NSCLC   

Questions discussed in this category

Will degree of PD-L1 status impact your decision? Would you ever offer to stage IB patients as per study enrollment?  Do AJCC v8 staging guideli...

Do you initially start with systemic therapy alone or do you proceed directly to chemo-radiation? 

Do you aim to give a total of 26 doses or do you stop at one year from first dose no matter how many were given?

How do you prescribe a steroid taper? If it is grade 2, would you keep them on low dose prednisone while continuing? When do you feel comfortable re-c...

Do you recommend or make any modifications in the PACIFIC regimen for patients > 75 years of age?

Do you feel it is important to start durvalumab within 14 days of completing cCRT?  What real life challenges do you face in doing so and wh...

Papers discussed in this category

Lancet (London, England), 2009-08-01

Lung Cancer,

Lancet Oncol., 2008 Jun 24

The New England journal of medicine, 2018-12-13

JAMA oncology, 2019-07-01

N Engl J Med, 2017 Nov 16

N Engl J Med, 2020 Sep 19

Lancet (London, England), 2019-05-04

J Clin Oncol, 2021 Apr 19

Lancet, 2021 Sep 20

The Lancet. Oncology, 2015-02

J. Clin. Oncol., 2015 Nov 02

N Engl J Med, 2022 Apr 11

Eur Respir J, 2005 Aug

N Engl J Med, 2023 Jun 28

The New England journal of medicine, 2018 Apr 16

The Lancet. Oncology, 2020 May 07

Translational lung cancer research, 2019 Sep

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2009 Aug 21

Cancers, 2021 Sep 26

Clinical lung cancer, 2023 Jul 25

ERJ open research, 2020 Feb 17

Clinical Medicine Insights. Oncology, 2023 Feb 14