How would you manage metastatic small cell/neuroendocrine bladder cancer after response to 6 cycles of platinum/etoposide?
If any clinical benefit (ie. CR, PR or SD) would you consider switch maintenance avelumab, surveillance until progression, or an alternate regimen?
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What would you do for a patient after response to platinum-etoposide for metastatic small cell bladder cancer?
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1 Answer
Mednet MemberInvited Expert
Medical Oncology · AdventHealth Cancer Institute
Answered on
I would consider maintenance avelumab in patients with metastatic small cell carcinoma of the bladder achieving stable or responding disease after platinum-etoposide. Notably, the JAVELIN Bladder-100 trial that led to the approval of maintenance avelumab included urothelial carcinoma and not predomi...
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