Questions discussed in this category

Does a progressing kappa/lambda ratio > 100 at any point in time warrant treatment, or does one wait to treat patients in the setting of a slowly i...

For example: shorten IMiD duration each cycle, add scheduled G-CSF, add antibacterial prophylaxis, etc.

If any clinical benefit (ie. CR, PR or SD) would you consider switch maintenance avelumab, surveillance until progression, or an alternate regimen?

Molecular profiling revealed no targetable alterations, however tumor mutational burden was >10 mut/Mb.

Patient has progression of liver metastases while on pembrolzumab/axitinib. ECOG PS 1 and limited comorbidities.

What clinicopathological features would need to be present for you to recommend adjuvant chemotherapy? Would you treat pT3 disease? Any specific histo...

Specifically, would you offer salvage radiation to a patient who underwent a prostatectomy with PLND and had a post-op PSA of 12 with pathology reveal...

Papers discussed in this category

Journal of clinical pharmacology, 2010-04

BJU Int, 2011 Oct

Anticancer Drugs,

The New England journal of medicine, 2017-07-27

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-12-10

JAMA Oncol, 2021 Feb 18

International journal of radiation oncology, biology, physics, 2018-10-01

Lancet, 2021 May 07

N. Engl. J. Med., 2016-10-13

N. Engl. J. Med., 2017-07-27

Lancet, 2020 Sep 28

Lancet Oncol,

Lancet Oncol,

J Urol, 2020 Apr 13

Eur J Nucl Med Mol Imaging, 2020 Aug 12

J Urol,

J Clin Oncol, 2021 Feb 02

Lancet Oncol, 2020 Jan

Eur J Cancer, 2020 Jun 27

The New England journal of medicine, 2018-11-08

Eur J Haematol, 2021 Aug 11

Lancet Oncol, 2020 Oct 29

Blood Adv, 2021 Sep 01


Am J Hematol, 2021 Jul 05

Int J Cancer, 2018 May 10

European urology, 2019-06

N Engl J Med, 2020 Sep 18

Cancer, 2020 Nov 20

BJU international, 2011-09

Cancer, 2009-09-15

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-04-01

Clinical genitourinary cancer, 2016-02

Cancer, 2019-05-01

European urology, 2017-07

Int Urol Nephrol, 2007 Mar 02

Clin Genitourin Cancer, 2017 Jul 22

Clin Genitourin Cancer, 2020 Feb 08

Eur Urol, 2019 Nov 08

J Clin Oncol,

Clin Lymphoma Myeloma Leuk, 2020 Mar 07

Clin Lymphoma Myeloma Leuk, 2021 Jul 18

J Urol, 2020 Jul

Clin Cancer Res, 2020 Jan 22

Cancer, 2021 Apr 21

Blood, 2011-09-15

Haematologica, 2011 Dec 01

Cancer Chemother Pharmacol, 2016 Jun 10

Clin Cancer Res, 2020 Aug 17

Lancet Oncol, 2014 Oct 26

Blood cancer journal, 2016-07-29

Leukemia, 2022 Apr 11