Are there circumstances where you would recommend every 6 week dosing schedule for pembrolizumab monotherapy?  

I am considering every 6 week pembrolizumab dosing in patients >70 years old in whom I want to reduce clinic visits for, especially in the context of the COVID-19 pandemic. This schedule was approved in Europe based on modeling/simulation (https://ascopubs.org/doi/abs/10.1200/JCO.2018.36.15_suppl.3062), but the FDA rejected the every 6 week dosing in February 2020. 



Answer from: Medical Oncologist at Academic Institution

Answer from: Medical Oncologist at Community Practice
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