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What chemotherapy regimen do you recommend with radiation therapy for cervical esophageal squamous cell carcinoma?

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Mednet Member
Mednet Member
Medical Oncology · University of Texas MD Anderson Cancer Center

I would use weekly carboplatin/paclitaxel in this setting. Fluoropyrimidine + platinum is reasonable but will likely be more toxic, and I'm not aware of any data indicating that it's a more effective regimen.

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Mednet Member
Mednet Member
Medical Oncology · Dana-Farber Cancer Institute

I have typically offered concurrent FOLFOX rather than 5FU/Cisplatin for definitive therapy of proximal esophageal cancers- either adenocarcinoma or squamous cell carcinoma. The former regimen is more likely to cause neuropathy but in my experience has been more tolerable than 5FU/Cisplatin. While n...

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