What systemic therapy do you recommend for prostate cancer pelvic nodal recurrence on PSMA PET-CT after prostatectomy and salvage radiation?

Topics: Radiation Oncology • Genitourinary Cancers • Prostate Cancer • Medical Oncology • NCI-CCC Tumor Board Question • Duke • NCI-CCC GU Tumor Board Question • Duke GU Tumor Board

If ADT +/- ARPI + RT, what duration of systemic therapy do you recommend?

Answer from: Medical Oncologist at Community Practice

If the LNs are not measurable on conventional imaging and can be covered in the radiation fields, then for now I treat as high risk salvage setting. Usually suggest 2 years ADT and radiation. If the LNs cannot be covered in the radiation fields, or are measurable, then would also escalate AR-target...

Comments

Radiation Oncologist at Allan Blair Cancer Centre
Thanks for that detailed response! Unfortunately I...

Radiation Oncologist at Sanford Health
Attard et al., PMID 34953525. Phase 3 randomized t...

Radiation Oncologist at OhioHealth Radiation Oncology
I can't help but feel that until results show an a...

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