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What systemic therapy do you recommend for prostate cancer pelvic nodal recurrence on PSMA PET-CT after prostatectomy and salvage radiation?

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Mednet Member
Mednet Member
Medical Oncology · UTSouthwestern Medical Center

If the LNs are not measurable on conventional imaging and can be covered in the radiation fields, then for now I treat as high risk salvage setting. Usually suggest 2 years ADT and radiation.

If the LNs cannot be covered in the radiation fields, or are measurable, then would also escalate AR-targete...

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What systemic therapy do you recommend for prostate cancer pelvic nodal recurrence on PSMA PET-CT after prostatectomy and salvage radiation? | Mednet