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What would be your approach in a patient who presented with a solitary brain metastasis that resolved after chemo without local therapy?

Would you offer consolidative brain SRS, SRS + consolidative RT to the primary (e.g. lung), consolidative RT to the primary alone?
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How would you manage a solitary brain met that resolves after chemo alone?

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2 Answers
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Mednet MemberInvited Expert
Radiation Oncology · City of Hope
Answered on

While I have not had this happen with my patients receiving chemotherapy alone, in the era of targeted therapies for oncogenic driver mutated NSCLC, we have had some great intracranial response rates with systemic alone, and for these, I have held off SRS to evaluate response. In someone with a comp...

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Mednet Member
Mednet Member
Medical Oncology · Kaiser Permanente Medcl Center
Answered on

I have seen long term responses

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