What would be your approach in a patient who presented with a solitary brain metastasis that resolved after chemo without local therapy?

While I have not had this happen with my patients receiving chemotherapy alone, in the era of targeted therapies for oncogenic driver mutated NSCLC, we have had some great intracranial response rates with systemic alone, and for these, I have held off SRS to evaluate response. In someone with a comp...

I have seen long term responses