CNS Disease

Questions discussed in this category

How would you consolidate a patient with primary refractory double hit lymphoma with secondary CNS involvement?

At the time of initial diagnosis, there was no clear CNS involvement. When it became clinically apparent disease was refractory to EPOCH, there was CS...

2 Answers available

Do you routinely prescribe memantine for patients who will be receiving hippocampal sparing whole brain RT if they are already on donepezil, or is donepezil alone sufficient?

1 Answer available

What would be your approach in a patient who presented with a solitary brain metastasis that resolved after chemo without local therapy?

Would you offer consolidative brain SRS, SRS + consolidative RT to the primary (e.g. lung), consolidative RT to the primary alone?

2 Answers available

What is the risk of serious bacterial infection in a febrile solid tumor patient who has not yet started cancer-directed therapy and has normal cell counts with no central line?

1 Answer available

Is there a dose to the lens that would be a contraindication for future cataract surgery?

1 Answer available

Is it safe to give large fraction stereotactic irradiation for brain metastases concurrently with VEGF inhibitors?

0 Answers available

Would you recommend adjuvant radiotherapy for recurrent paraganglioma with lymph node involvement treated with salvage neck dissection with no residual disease?

Would the rate of growth, number of nodes involved, size of nodes, ENE etc. affect your decision? What volume and dose would you recommend?

1 Answer available

What features or presentations would prompt you to offer radiotherapy for paraganglioma vs. continued surveillance?

Aside from symptomatic disease, is there a certain growth cutoff or other criteria that would be a trigger for treatment?

1 Answer available

Are there any circumstances in which you would recommend adjuvant chemoradiation for resected olfactory neuroblastoma?

4 Answers available

Are there any features that help differentiate Sjogren's-related CNS demyelinating plaques from multiple sclerosis in a patient with primary Sjogren's syndrome?

1 Answer available

Papers discussed in this category

Multiple sclerosis (Houndmills, Basingstoke, England), 2014-01

Limited utility of current MRI criteria for distinguishing multiple sclerosis from common mimickers: primary and secondary CNS vasculitis, lupus and Sjogren's syndrome.

Ann. Neurol., 2018 Feb 15

Central vein sign differentiates Multiple Sclerosis from central nervous system inflammatory vasculopathies.

Int. J. Radiat. Oncol. Biol. Phys., 2011 Jun 15

Esthesioneuroblastoma: is there a need for elective neck treatment?

Cancer, 2004-12-01

Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype.

Blood advances, 2023 Sep 26

Real-world results of CAR T-cell therapy for large B-cell lymphoma with CNS involvement: a GLA/DRST study.

CNS Disease

Questions discussed in this category

Papers discussed in this category

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