Pediatric Hematology/Oncology

General Rheumatology

Questions discussed in this category

Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?

Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

2 Answers available

Is there any indication for IVIG in immunocompromised patients with only decreased IgM and/or IgA levels?

5 Answers available

What is the recommended fungal workup in an immunocompromised patient after 5 days of persistent fever?

Do you involve additional specialists, such as ENT, to further evaluate? Is there a particular algorithm followed by your institution, or it is just d...

3 Answers available

Can lupus anticoagulant be positive despite a normal aPTT?

How often does this occur and does this lower your suspicion for a "true" or clinically significant lupus anticoagulant?

1 Answer available

When would you consider using G-CSF in patients with rheumatic disease who have received cyclophosphamide?

2 Answers available

Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?

1 Answer available

How do you utilize cytokine panels in your clinical practice?

Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...

1 Answer available

What is your approach to working up diarrhea in an immunocompromised patient?

1 Answer available

Does IVIG or subcutaneous Ig interfere with monoclonal antibody therapy (i.e. dupilumab, infliximab, rituximab, etc)?

How should IVIG and either biologic injections or infusions be spaced?

2 Answers available

Is there a concern for the potential of future congenital malformations in offspring when preservation of eggs and sperm is done AFTER cyclophosphamide treatment given that it is an alkylating agent?

1 Answer available

How do you approach evaluation and management of arthralgia in a patient after CAR-T cell therapy?

1 Answer available

How do you approach dosing of anakinra in MAS?

1 Answer available

Do you typically see peripheral neuropathy in patients with castleman syndrome?

2 Answers available

Is rituximab for refractory ITP contraindicated in the setting of an active COVID infection, particularly in a patient with asymptomatic COVID?

2 Answers available

Do you recommend continuous antibiotic prophylaxis for patients on complement inhibitors such as eculizumab?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

3 Answers available

In patients who develop a VTE, what conditions do you consider as persistent, provoking risk factors, and at what point are they controlled enough to stop anticoagulation?

I.e., what constitutes well-controlled cancer, IBD, nephrotic syndrome, etc. What other diseases do you put in this category (obesity, autoimmune dise...

1 Answer available

Do you recommend routine use of Evusheld for pre-exposure prophylaxis for patients on immunosuppression?

Does treatment with B-cell depletion and/or negative anti-spike antibody status despite COVID mRNA vaccination influence your decision?

1 Answer available