Radiation Oncology

Re-irradiation   

Questions discussed in this category


Is there any further benefit of hyperthermia monotherapy, for example, continuation of hyperthermia after the course of radiation has completed?

Does the time interval between the intial RT and recurrence influence your decision? What time interval would you feel is appropriate? What dose would...

How does grade, margin status, and previous radiation dose factor into the recommendation? 

Assuming CSF is negative for neoplastic cells would you: Re-irradiate gross disease only? Re-irradiate posterior fossa only? Re-irradiate the entir...

Do you assume some recovery since the prior course of RT? If so, how much over what time period?

What dose fractionation and volume do you use? What factors influence your decision?

If the patient had RT 3 months prior and had a revision surgery, would you offer RT again? If so, which dose and fractionation would you use?

Does your recommendation change depending on the disease-free interval?

For example, would you treat the entire length of the femur after prophylactic intramedullary rod fixation for a femoral neck metastasis?

If a WHO II glioma was treated with RT and recurs and is now a WHO III glioma would you retreat with radiation?  What would be your target volume...

If a patient has increasing FLAIR and T1 enhancing activity, should both be included in the treatment volume? What factors to you consider in making y...

Is there any literature supporting that a gentle fractionation/bid regimen (i.e., 1.5Gy bid x 30 = 45Gy) is safer than a standard fractionation  ...

Eight years after brachytherapy for a low risk prostate cancer, a patient has unresectable high grade squamous cell carcinoma of the bladder. Should I...


Papers discussed in this category


J Clin Oncol, 2010 Jun 20

J Neurooncol, 2014 Jan

Pract Radiat Oncol, 2015 Apr 6

Radiother Oncol, 2016-10-01

Int J Radiat Oncol Biol Phys, 2011 Mar 15

J. Clin. Oncol., 2008-12-01

J Clin Oncol, 2009 Apr 1

Acta Oncol, 2006-01-01

J. Cancer Res. Clin. Oncol., 2015-07-01

Semin Radiat Oncol, 2017-07-01

J Neurooncol, 2012 Jan

Am J Clin Oncol, 2012 Feb

Eur. J. Cancer, 2017-03-01