Dementia

Questions discussed in this category

When, if ever, do you consider using dronabinol to treat agitation in dementia?

How do you approach informed consent when prescribing dronabinol in patients with dementia? Are there any particular risks or adverse effects that you...

2 Answers available

How do you treat agitation in progressive supranuclear palsy?

Would you consider benzodiazepines for agitation in progressive supranuclear palsy? What other treatment strategies would you consider?

1 Answer available

What is your antipsychotic of choice and general titration regimen in the outpatient setting for a patient with dementia and behavioral disturbances (assuming reversible causes such as urinary retention, constipation, etc. have been addressed)?

3 Answers available

How do you approach biopsy and management decisions for a rapidly enlarging periocular tumor in an elderly patient with dementia who is unable to communicate and whose family prefers to avoid aggressive treatment?

1 Answer available

In older adults with mild cognitive impairment, do you ever prescribe cholinesterase inhibitors and/or memantine?

How do you counsel patients on this off-label use?

7 Answers available

How have the results of the U.S. POINTER study involving multidomain lifestyle interventions to protect cognitive function influenced your practice?

Was the change that was noted in the trial clinically meaningful?Study reference: Baker et al., PMID 40720610

1 Answer available

How do you differentiate cognitive impairment from normal age-related cognitive decline?

Especially in the era of novel AD biomarkers (blood-based, CSF, PET scans), AD treatments, and new definitions of Alzheimer's (Alz Association 2025) -...

2 Answers available

What treatment options are there for uremic pruritus in an elderly patient with risk of sundowning?

How can treatments be combined or escalated?

2 Answers available

How do you select between antipsychotics in the treatment of delirium refractory to nonpharmacological management in hospitalized older adults with dementia?

From a geriatrics harm-reduction standpoint, can we recommend any particulars regarding dosing or selection of therapies when used as a last resort?

2 Answers available

How do you approach the management of older adult patients with dementia who repeatedly aspirate with oral intake but whose family/HCP may be unwilling to accept the aspiration risk associated with comfort eating?

Considering poor outcomes/lack of long-term benefit for NGT/PEG placement in this population.

2 Answers available

How do you determine whether to continue anti-dementia medications (such as cholinesterase inhibitors) for patients with dementia when enrolling in hospice?

3 Answers available

What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?

1 Answer available

When is it useful to test for multiple amyloid-related biomarkers for patients undergoing work-up for cognitive impairment?

E.g., amyloid PET, CSF amyloid, blood-based amyloid.

1 Answer available

How do you manage sleep disturbances in patients with Alzheimer’s disease without relying heavily on deliriogenic medications?

2 Answers available

What patient factors most strongly influence your decision to start biologic agents in mild cognitive impairment?

Specifically, what guidelines do you use to help determine this (if any)?

1 Answer available

How do stroke-risk considerations affect your use of atypical antipsychotics for patients with dementia?

Related Q&A on antipsychotics in Alzheimer's.In light of the publication from Choma et al., PMID 41063545.

2 Answers available

Are there scenarios in which you would advise using benzodiazepines for the treatment of hyperactive delirium?

1 Answer available

How do you choose among SSRIs and dosing strategies for the management of behavioral and psychological symptoms of dementia?

What factors might drive decisions for different SSRIs and/or doses?

1 Answer available

What is your approach to deprescribing cholinesterase inhibitors and/or memantine in advancing stages of dementia?

2 Answers available

What would be your approach to the consideration of the use of antiamyloid monoclonal antibodies for nonamnestic Alzheimer's disease with a positive biomarker for brain amyloid pathology?

E.g., primary progressive aphasia

2 Answers available

How do you approach evaluating sudden mental status changes in telepsychiatry patients, particularly older adults, when medical causes such as infection or metabolic disturbance may be contributing factors?

What red flags prompt you to recommend urgent in-person evaluation? Are there particular strategies or screening questions you have found helpful to d...

1 Answer available

Would you recommend a GLP-1 agonist as an option to reduce the risk of dementia in patients with a strong family history?

As studied in Tang H, Donahoo WT, DeKosky ST, et al. GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related De...

1 Answer available

How do you approach balancing the treatment of urinary incontinence with anticholinergic medications with the use of cholinesterase inhibitors in dementia?

1 Answer available

How do you approach individualizing A1c goals in patients with dementia?

2 Answers available

What is your approach to determining eligibility for hospice in persons with Alzheimer's disease?

1 Answer available

What are your preferred strategies for managing sundowning in patients with moderate Alzheimer’s disease?

2 Answers available