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Geriatric Medicine   

Questions discussed in this category

What is your clinical approach to deprescribing vs continuing low-dose aspirin used for primary prevention in older adults who are already taking this medication?
Are there any pearls for strong factors that would push you towards vs away from deprescribing?
1 Answer available
How would you approach the consideration of continuing or ceasing colonoscopy for colon cancer screening in a relatively fit man in his 80s without a history of polyps on prior colonoscopies?
1 Answer available
In older adults with mild cognitive impairment, do you ever prescribe cholinesterase inhibitors and/or memantine?
How do you counsel patients on this off-label use?
1 Answer available
In outpatient primary care settings, would you recommend routinely checking Cystatin-C as a marker of renal function in older adults?
2 Answers available
What is the role for checking uric acid levels in evaluation of SIADH in hospitalized older adults?
1 Answer available
When considering deprescribing antihypertensives in older patients, how do you approach prioritization of which antihypertensives to target first?
1 Answer available
How do you approach the choice of pharmacological therapy when treating insomnia in older adults in the outpatient setting with a high falling risk?
Are there any pearls re: which therapies that may be slightly safer vs to be strongly avoided?
1 Answer available
What is your approach to counseling severely frail older adults regarding their planning for invasive life-sustaining therapy?
2 Answers available
How would you approach counseling an older patient with significant hearing loss and nonadherence to use of hearing aids?
2 Answers available
How have the results of the U.S. POINTER study involving multidomain lifestyle interventions to protect cognitive function influenced your practice?
Was the change that was noted in the trial clinically meaningful?Study reference: Baker et al., PMID 40720610
1 Answer available
How do you approach the management of newly discovered prediabetes in adults over the age of 65?
2 Answers available
Should we be recommending a specific daily protein intake to prevent sarcopenia in geriatric patients, or do you find it more beneficial to focus on encouraging activity within their mobility limitations to preserve muscle mass?
1 Answer available
Do you have any pearls for how to manage OSA with CPAP in older adults with cognitive impairment?
1 Answer available
What is your approach to counseling older patients and their families regarding expected recovery of aphasia following a large hemispheric stroke?
2 Answers available
Which anticoagulant (DOAC or Warfarin) would you recommend in the case of a 70-year-old male with persistent atrial fibrillation and history of rheumatic mitral stenosis now status post bioprosthetic MVR?
1 Answer available
How are you incorporating the newer RCT data suggesting no mortality benefit to indefinite beta-blocker therapy for patients who are several years out from an MI with preserved LVEF and no angina or arrhythmia?
As per the REDUCE-AMI trial. Are you routinely de-prescribing, selectively stopping based on symptoms or risk profile, or still continuing by def...
1 Answer available
How do you approach decision-making around initiation of osteoporosis therapy in patients with advanced dementia?
1 Answer available
What practical next steps would you recommend once identifying loneliness in an older adult patient?
1 Answer available
How do you differentiate cognitive impairment from normal age-related cognitive decline?
Especially in the era of novel AD biomarkers (blood-based, CSF, PET scans), AD treatments, and new definitions of Alzheimer's (Alz Association 2025) -...
2 Answers available
What treatment options are there for uremic pruritus in an elderly patient with risk of sundowning?
How can treatments be combined or escalated?
2 Answers available
How do you select between antipsychotics in the treatment of delirium refractory to nonpharmacological management in hospitalized older adults with dementia?
From a geriatrics harm-reduction standpoint, can we recommend any particulars regarding dosing or selection of therapies when used as a last resort?
2 Answers available
How do you counsel older adults regarding the use of melatonin (dose and timing) for sleep-related problems?
2 Answers available
How do you approach the management of older adult patients with dementia who repeatedly aspirate with oral intake but whose family/HCP may be unwilling to accept the aspiration risk associated with comfort eating?
Considering poor outcomes/lack of long-term benefit for NGT/PEG placement in this population.
2 Answers available
What strategies do you find helpful in advanced care planning with patients/families who are very "miracle" centered?
For example, prolonging life-sustaining measures as they "wait for a miracle" of an unrealistic outcome. 
2 Answers available
How do you determine whether to continue anti-dementia medications (such as cholinesterase inhibitors) for patients with dementia when enrolling in hospice?
3 Answers available
How soon after a fracture would it be safe to start anti-resorptive therapy?
3 Answers available
What patient factors are most important when considering who needs a broader workup for osteoporosis prior to starting therapy?
Do you routinely rule out secondary causes of osteoporosis (i.e., TSH) in all patients prior to starting therapy? If you work up all patients, what la...
1 Answer available
What are your thoughts about lion's mane supplementation to slow the decline or improve cognitive capacity for those at risk of dementia?
1 Answer available
What is your preferred approach to obtaining an objective measure of frailty on physical exam in a primary care practice setting?
For example, do you use Timed Up and Go? Chair stands? Other measures?
1 Answer available
When is it useful to test for multiple amyloid-related biomarkers for patients undergoing work-up for cognitive impairment?
E.g., amyloid PET, CSF amyloid, blood-based amyloid.
1 Answer available
How do you manage sleep disturbances in patients with Alzheimer’s disease without relying heavily on deliriogenic medications?
2 Answers available
What are some practical steps physicians can take to optimize mobility and reduce falls in hospitalized patients?
1 Answer available
Do you recommend starting a statin in patients above 75 years old with diabetes but no known ASCVD?
3 Answers available
Would you consider transitioning patients older than 75 years of age with coronary disease from statins and/or other lipid-lowering agents to PCSK9 inhibitors given concerns for polypharmacy, provided their LDL levels remain at or below goal?
2 Answers available
How do you counsel older adults regarding the use, dosing, and safety of CBD-containing products for insomnia?
1 Answer available
How would you approach the management of asymptomatic ALT and GGT elevation in an older adult patient with depression with psychosis and without history of hepatitis who recently had dose of quetiapine increased and new initiation of SNRI?
1 Answer available
How do you decide between anticoagulation and observation for an incidentally detected subsegmental pulmonary embolism in elderly patients with a history of gastrointestinal bleeding?
7 Answers available
How do you approach the management of extremely low LDL levels in older adult patients receiving statin therapy for primary prevention of cardiovascular disease?
1 Answer available
How do you choose among SSRIs and dosing strategies for the management of behavioral and psychological symptoms of dementia?
What factors might drive decisions for different SSRIs and/or doses?
1 Answer available
Do you routinely adjust your interpretation of SLUMS and/or MOCA tests in patients depending on their level of education?
2 Answers available
How do you approach treating depressive symptoms in an older adult already taking an SSRI?
Would you consider adding a second medication versus uptitrating the original SSRI?
1 Answer available
What is your approach to deprescribing cholinesterase inhibitors and/or memantine in advancing stages of dementia?
2 Answers available
What is your approach to bisphosphonate use in patients with advanced chronic kidney disease and osteoporosis?
3 Answers available
What are the best practices for optimizing transitions from hospital to skilled nursing facilities for older adult patients, with specific regard to adapting hospital medication regimens to the skilled nursing facility setting?
3 Answers available
What would be your approach to the consideration of the use of antiamyloid monoclonal antibodies for nonamnestic Alzheimer's disease with a positive biomarker for brain amyloid pathology?
E.g., primary progressive aphasia
2 Answers available
How do you approach Vitamin D testing and supplementation in older adults following a fragility fracture?
1 Answer available
What are some practical tips in distinguishing between metabolic bone disease due to chronic kidney disease and osteoporosis?
1 Answer available
What is your approach to initiation of mirtazapine for appetite stimulation and depression in older adults, both in terms of starting dose and titration?
2 Answers available
How would you recommend approaching screening for elder abuse in the primary care setting for older adults?
Are there any especially recommended screening instruments/resources?
1 Answer available
What is your approach to the use of GLP-1 agonists in older adults with diabetes with or at risk of sarcopenia?
3 Answers available
Would you recommend a GLP-1 agonist as an option to reduce the risk of dementia in patients with a strong family history?
As studied in Tang H, Donahoo WT, DeKosky ST, et al. GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related De...
1 Answer available
For patients over 70 with elevated ASCVD risk but no prior cardiovascular events, do you ever recommend continuing or initiating low-dose aspirin?
Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication
1 Answer available
What is your systolic blood pressure target for patients over 80 with frailty and multiple comorbidities?
1 Answer available
How can we approach tapering or discontinuing biologic DMARDs in patient in their 80s with well controlled rheumatoid arthritis?
3 Answers available
What is your antipsychotic of choice and general titration regimen in the outpatient setting for a patient with dementia and behavioral disturbances (assuming reversible causes such as urinary retention, constipation, etc. have been addressed)?
2 Answers available
How do you approach balancing the treatment of urinary incontinence with anticholinergic medications with the use of cholinesterase inhibitors in dementia?
1 Answer available
How do you approach individualizing A1c goals in patients with dementia?
2 Answers available
What suggestions for environmental modifications do you find most helpful to reduce the risk of falls in the geriatric population?
Are there certain modifications to the home or aid devices that you commonly recommend? Some that are more cost-effective? 
1 Answer available
Do you consider using buspirone for the management of anxiety in older patients?
4 Answers available
What is your approach to deprescribing gabapentinoids so as to prevent withdrawal effects?
1 Answer available
What is your approach to determining eligibility for hospice in persons with Alzheimer's disease?
1 Answer available
How do you counsel patients who are concerned that discontinuation of certain chronic medications may actually perpetuate suffering at the end of life?
Do you ever continue medications such as rate-control agents for tachyarrhythmias, anticoagulation for blood clots, immunosuppression to prevent trans...
1 Answer available
How do you decide when to initiate medical workup (e.g., thyroid, B12, infection) in a geriatric patient experiencing new onset or worsening low mood?
2 Answers available
Do you routinely prescribe vitamin D to reduce the risk of fall-related fractures in elderly patients regardless of their serum levels?
1 Answer available
For elderly patients (i.e. older than 80) with only one documented episode of paroxysmal atrial fibrillation following a stress event (such as acute illness/steroid administration) and a CHADsVASc score greater than 1, how would you counsel them on the risks/benefits of anticoagulation and subsequent monitoring for afib recurrence?
6 Answers available
What is the next best osteoporosis treatment option for patients who completed 2 years of teriparatide, but has contraindication to bisphosphosnate therapy (e.g. history of atypical femur fracture)?
1 Answer available
Is there any benefit in maintaining statin or aspirin therapy in patients >75 years old with stable, multivessel ischemic heart disease in light of challenges encountered with polypharmacy?
2 Answers available
Would you use a parathyroid hormone analog for treatment of osteoporosis in a patient with mildly elevated AlkPhos of unclear etiology?
1 Answer available
Would you start romosozumab in an active smoker?
1 Answer available
During treatment of severe osteoporosis with PTH analogs (abaloparatide), would a rise in alkaline phosphatase level >200 (in the setting of normal GGT) warrant discontinuation of medication?
There is concern for elevation in alkaline phosphatase as a precursor for bone pathology, such as an increase in risk of bone malignancy, potentially ...
1 Answer available
How do you recommend counseling patients on the prognosis of advanced cancer as a generalist who is not highly specialized in cancer literature or cancer-directed therapies?
2 Answers available
For patients over 90 years old, is there any foreseeable benefit to undergoing left atrial appendage occlusion over permanent cessation of anticoagulation, particularly for those at high risk for major bleeding?
2 Answers available
Is it necessary to prescribe a steroid taper after two weeks of high-dose prednisone (60 mg daily)?
6 Answers available
When do you consider using aspirin 81 mg PO BID for VTE prophylaxis over other agents in patients with a fracture, considering recent trial data?
O'Toole et al., PMID 36652352
1 Answer available
How do you counsel non-diabetic patients who wish to start metformin to reduce the risk of developing dementia?
2 Answers available
What is your approach to a newly diagnosed LBBB in individuals >70 years old who are free of any signs or symptoms of heart disease and without other significant ASCVD risk factors besides age?
If the ECG was obtained prior to major orthopedic surgery (such as hip replacement) would that change your approach?
3 Answers available
Is a target TSH closer to the mid normal range justified in older individuals (age 70 or above) without any known cardiac ischemia or dysrhythmia or osteoporosis?
Is this recommended TSH target of 7 or higher based on the fact that globally iatrogenic hyperthyroidism is common in older individuals on levothyroxi...
1 Answer available
How do you approach revascularization in patients over 75 years with NSTEMI, given recent evidence from the SENIOR-RITA trial that an invasive strategy does not significantly reduce cardiovascular events compared to a conservative strategy?
Kunadian, et al., PMID 39225274
1 Answer available
Does aspirin dose (81 mg vs 325 mg) matter for secondary stroke prevention?
Should some patients get 325 mg instead of 81mg at least for a certain amount of time, such as patients in the acute phase of ischemic stroke or patie...
1 Answer available
Is there any role for 25-OH Vitamin D testing in patients older than 75 years old in the general population?
Demay, et al., PMID 38828931
2 Answers available
How do you approach selecting biologic therapy vs non-biologic DMARD (such as methotrexate) as initial therapy in patients with new RA diagnosis with significant erosive disease?
This question is part of a collaboration with RheumMadness and is specifically in reference to: NORD-STAR (Østergaard et al., PMID 3742364...
5 Answers available
How would you approach the work up of SLE in a patient over 80 years old?
How would you work up an elderly female with persistent anemia secondary to warm AIHA requiring almost monthly transfusion, with positive ANA,dsDNA (b...
3 Answers available
Do you typically screen every patient with headaches after the age of 60 with ESR?
6 Answers available
What criteria are used to choose a specific dose of aspirin in ischemic stroke?
We have seen 81 vs 162 vs 325 mg up to 1300 mg.
3 Answers available
What duration of dual antiplatelet therapy do you use for secondary prevention of ischemic stroke due to intracranial atherosclerotic disease?
While some have the practice of 90 days per SAMMPRIS trial, the lower rates of ischemic stroke in the medical therapy group were driven by events with...
8 Answers available
Do you recommend performing cognitive testing in the clinic to determine the blood pressure target in patients 80 years or older?
1 Answer available
Would you recommend AV fistula placement in a CKD Stage 5 patient who is over the age of 80?
2 Answers available
Would you recommend PFO closure in patients >60 years old with presumed paradoxical embolism as their mechanism of stroke?
2 Answers available
Do you recommend life long aspirin 81 mg daily for non-specific T2 white matter hyper-intensities on MRI brain?
7 Answers available
How do you manage myasthenia gravis in patients over the age of 90?
What is the best way to treat late onset myasthenia gravis (in this case, age >90)? Would the newer complement inhibitors be safe? Steroids in this...
2 Answers available
How do you approach a mildly positive finding on an autoimmune encephalitis panel when there is no other evidence of encephalitis (such as elevated CSF protein, abnormal imaging, or EEG findings)?
For example, a GAD65 Ab of 0.07 when the cut-off is 0.02. Does this answer change if you consider adult vs pediatric populations?
2 Answers available
Do you still plan to offer tofacitinib to RA patients over 65 if they have one or more additional CV risk factors?
2 Answers available
Given the "LDL Paradox", in which RA patients with the highest levels of inflammation can have ultra-low levels of LDL (<70), how do you approach initiation of statin therapy in these patients?
Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...
1 Answer available
In patients with thrombocytosis with negative MPN workup from peripheral blood and bone marrow, is there a role for daily 81mg aspirin or other treatment?
2 Answers available
What is your approach to checking serum vWF antigen levels in adult patients with CNS vasculitis for monitoring disease activity?
Small study in pediatric PACNS have evaluated this as a potential marker (Cellucci et al., PMID 22740622)
1 Answer available


Papers discussed in this category

Neurology, 2015-09-29
Dual antiplatelet therapy in stroke and ICAS: Subgroup analysis of CHANCE.
Stroke, 2017-08
Challenges in the Medical Management of Symptomatic Intracranial Stenosis in an Urban Setting.
Stroke, 2021 May 24
2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.
Lancet (London, England), 2014-01-25
Aggressive medical treatment with or without stenting in high-risk patients with intracranial artery stenosis (SAMMPRIS): the final results of a randomised trial.
Circulation, 2019-08-20
Time Course for Benefit and Risk of Clopidogrel and Aspirin After Acute Transient Ischemic Attack and Minor Ischemic Stroke.
Archives of neurology, 2009-06
Ganglionic acetylcholine receptor autoantibody: oncological, neurological, and serological accompaniments.
Muscle & nerve, 2013-04
Striational antibodies in a paraneoplastic context.
Muscle & nerve, 2016-08
P/Q- and N-type calcium-channel antibodies: Oncological, neurological, and serological accompaniments.
Muscle & nerve, 2017-07
GAD65 neurological autoimmunity.
Annals of neurology, 2017-07
Expanded phenotypes and outcomes among 256 LGI1/CASPR2-IgG-positive patients.
Front Neurol, 2019 Jun 06
Primary Angiitis of the Central Nervous System: New Potential Imaging Techniques and Biomarkers in Blood and Cerebrospinal Fluid.
The New England journal of medicine, 2013-03-21
Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.
Neurology, 2013-08-13
An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke.
The New England journal of medicine, 2017-09-14
Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.
Circ Cardiovasc Interv, 2022 Jun 23
Transcatheter Closure of Patent Foramen Ovale in Older Patients With Cryptogenic Thromboembolic Events.
JAMA, 2021 Dec 14
Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.
JAMA Neurol, 2020 Jul 01
Proposal for Updated Nomenclature and Classification of Potential Causative Mechanism in Patent Foramen Ovale-Associated Stroke.
JAMA Neurol, 2022 Nov 01
Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.
Circulation, 2016-11-22
Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association.
JAMA, 2022 Apr 26
Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.
JAMA, 2019-02-12
Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.
JAMA, 2019-08-13
Association of Intensive vs Standard Blood Pressure Control With Cerebral White Matter Lesions.
Kidney Int, 2019 Jan
Hemodialysis vascular access in the elderly-getting it right.
Lancet (London, England), 2018-08-04
Effects of aspirin on risks of vascular events and cancer according to bodyweight and dose: analysis of individual patient data from randomised trials.
Lupus, 2024 Jan 16
Complement C4d as a biomarker for systemic lupus erythematosus and lupus nephritis.
Arthritis care & research, 2022 Feb 08
A 79-Year-Old Female Patient With Altered Mental Status and Anemia.
Journal of the Endocrine Society, 2022 Dec 02
Perioperative Evaluation and Management of Patients on Glucocorticoids.
Diagnostics (Basel, Switzerland), 2021 Apr 20
Glucocorticoid Withdrawal-An Overview on When and How to Diagnose Adrenal Insufficiency in Clinical Practice.
The New England journal of medicine, 2024 Sep 01
Invasive Treatment Strategy for Older Patients with Myocardial Infarction.
The New England journal of medicine, 2023 Jan 19
Aspirin or Low-Molecular-Weight Heparin for Thromboprophylaxis after a Fracture.
JAMA, 2022 Aug 23
Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty: The CRISTAL Randomized Trial.
Lancet (London, England), 2015 Mar 12
A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial.
Journal of palliative medicine, 2012-02
Systematic review of cancer presentations with a median survival of six months or less.
Journal of the American Medical Directors Association, 2022 Mar 23
Post-Acute Care Outcomes and Functional Status Changes of Adults with New Cancer Discharged to Skilled Nursing Facilities.
Palliative medicine, 2022 Jul
The utility of the surprise question: A useful tool for identifying patients nearing the last phase of life? A systematic review and meta-analysis.
JAMA, 2021 Apr 13
Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
Journal of the American Geriatrics Society, 2025 Jan 29
Updating STEADI for Primary Care: Recommendations From the American Geriatrics Society Workgroup.
The journals of gerontology. Series A, Biological sciences and medical sciences, 2023 Jun 16
Nutritional Interventions: Dietary Protein Needs and Influences on Skeletal Muscle of Older Adults.
Mayo Clinic proceedings, 2000 Jan
The biology of aging.
Journal of the American Geriatrics Society, 2000 Jun
Epidemiology of sarcopenia.
Archives of general psychiatry, 2008 Dec
Incidence and recurrence of late-life depression.
Current nutrition reports, 2022 Sep 13
Is Vitamin D Important in Anxiety or Depression? What Is the Truth?
The New England journal of medicine, 2013-11-28
Edoxaban versus warfarin in patients with atrial fibrillation.
The New England journal of medicine, 2011-09-15
Apixaban versus warfarin in patients with atrial fibrillation.
The New England journal of medicine, 2011 Aug 10
Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2021 Feb 08
Safety of Oral Bisphosphonates in Moderate-to-Severe Chronic Kidney Disease: A Binational Cohort Analysis.
Current opinion in nephrology and hypertension, 2022 Jun 10
Clinical utility of bone turnover markers in patients with chronic kidney disease.
The Journal of clinical endocrinology and metabolism, 2022 Dec 17
Inpatient Zoledronic Acid and Integrated Orthopedic and Fracture Liaison Services Improve Osteoporosis Treatment Rates.
J Bone Miner Res, 2024 Aug 21
Zoledronic acid for hip fracture during initial hospitalization.
J Clin Endocrinol Metab, 2023 Oct 18
Safety of Inpatient Zoledronic Acid in the Immediate Postfracture Setting.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2018-02
A Systematic Review of Practice Guidelines and Recommendations for Discontinuation of Cholinesterase Inhibitors in Dementia.
JAMA internal medicine, 2025 May 01
Continued Use of Cholinesterase Inhibitors and Memantine in Hospice.
Alzheimer's & dementia (New York, N. Y.), 2022 Jan 31
CCCDTD5 recommendations on the deprescribing of cognitive enhancers in dementia.
The Medical journal of Australia, 2019 Feb 16
Deprescribing cholinesterase inhibitors and memantine in dementia: guideline summary.
Arthritis Rheumatol, 2021 Jul
2021 American College of Rheumatology Guideline for the Treatment of Rheumatoid Arthritis.
Rheumatology (Oxford, England), 2023 Oct 19
A real-world 2-year prospective study of medication tapering in patients with well-controlled rheumatoid arthritis within the rheumatoid arthritis medication tapering (RHEUMTAP) cohort.
Arthritis research & therapy, 2015 Aug 03
Sustained biologic-free and drug-free remission in rheumatoid arthritis, where are we now?
Arthritis and rheumatism, 2009 Aug
Prevalence of and predictive factors for sustained disease-modifying antirheumatic drug-free remission in rheumatoid arthritis: results from two large early arthritis cohorts.
The Cochrane database of systematic reviews, 2018 Aug 23
Impact of medication reconciliation for improving transitions of care.
Journal of pain and symptom management, 2018-03
"They Need to Have an Understanding of Why They're Coming Here and What the Outcomes Might Be." Clinician Perspectives on Goals of Care for Patients Discharged From Hospitals to Skilled Nursing Facilities.
Journal of general internal medicine, 2023 Oct 02
Hospitalists Improving Transitions of Care Through Virtual Collaborative Rounding with Skilled Nursing Facilities-the HiToC SNF Study.
Journal of pain and symptom management, 2002-05
An open-label, crossover trial of mirtazapine (15 and 30 mg) in cancer patients with pain and other distressing symptoms.
Annals of internal medicine, 2025 Sep 30
Trends in Dispensed Gabapentin Prescriptions in the United States, 2010 to 2024.
British journal of clinical pharmacology, 2023 Jun 13
Deprescribing interventions for gabapentinoids in adults: A scoping review.
Journal of the American Geriatrics Society, 2013 Sep
Gabapentin withdrawal: case report in an older adult and review of the literature.
The Cochrane database of systematic reviews, 2006-07-19
Azapirones for generalized anxiety disorder.
Psychiatry and clinical neurosciences, 2010 Feb 01
Randomized, single-blind, trial of sertraline and buspirone for treatment of elderly patients with generalized anxiety disorder.
Basic & clinical pharmacology & toxicology, 2023 Jun 20
Serotonin syndrome-A focused review.
Ochsner journal, 2013 Winter
Serotonin syndrome.
The American journal of psychiatry, 2016-05-01
Heterogeneity of Treatment Response to Citalopram for Patients With Alzheimer's Disease With Aggression or Agitation: The CitAD Randomized Clinical Trial.
The American journal of psychiatry, 2016-05-01
Effects of Citalopram on Neuropsychiatric Symptoms in Alzheimer's Dementia: Evidence From the CitAD Study.
JAMA, 2014 Feb 19
Effect of citalopram on agitation in Alzheimer disease: the CitAD randomized clinical trial.
Frontiers in aging neuroscience, 2023 Mar 03
Comparative efficacy and safety of antidepressant therapy for the agitation of dementia: A systematic review and network meta-analysis.
Journal of Alzheimer's disease : JAD, 2020
The Efficacy of Sertraline, Escitalopram, and Nicergoline in the Treatment of Depression and Apathy in Alzheimer's Disease: The Okayama Depression and Apathy Project (ODAP).
Journal of the American Geriatrics Society, 2025 Apr 28
Treatment of Inappropriate Sexual Behavior in Persons With Dementia: A Systematic Review.
Journal of the American Geriatrics Society, 2016 Mar 23
Antipsychotic Medication for Prevention and Treatment of Delirium in Hospitalized Adults: A Systematic Review and Meta-Analysis.
The Cochrane database of systematic reviews, 2018 Jun 18
Antipsychotics for treatment of delirium in hospitalised non-ICU patients.
The journal of nutrition, health & aging, 2008 May
Importance of vitamin D in hospital-based fracture care pathways.
The New England journal of medicine, 2022 Jul 28
Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults.
Metabolism open, 2024 Jul 16
Effect of vitamin D on risk of falls and fractures - The contribution of recent mega-trials.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021 May 20
How can the orthopedic surgeon ensure optimal vitamin D status in patients operated for an osteoporotic fracture?
Geriatric orthopaedic surgery & rehabilitation, 2011 May
Is supplementation of vitamin d beneficial for fracture healing? A short review of the literature.
Diabetes research and clinical practice, 2021 Mar 08
GLP-1 receptor agonists and SGLT2 inhibitors for older people with type 2 diabetes: A systematic review and meta-analysis.
Journal of diabetes, 2025 Jun
Monitoring Sarcopenia With Incretin Receptor Activator Treatment.
Annals of internal medicine, 2021 Nov 23
Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation : A Multicenter Prospective Cohort Study.
JAMA, 2011-09-28
Efficacy and comparative effectiveness of atypical antipsychotic medications for off-label uses in adults: a systematic review and meta-analysis.
Drugs & aging, 2001
Hypertension in the Very Elderly Trial (HYVET): protocol for the main trial.
Circulation research, 2019 Mar 29
Hypertension Management in Older and Frail Older Patients.
The Cochrane database of systematic reviews, 2014-03-21
Pharmacotherapies for sleep disturbances in Alzheimer's disease.
Translational psychiatry, 2022 Apr 01
Sleep in Alzheimer's disease: a systematic review and meta-analysis of polysomnographic findings.
Journal of sleep research, 2020 Dec 02
Pharmacological and non-pharmacological interventions to enhance sleep in mild cognitive impairment and mild Alzheimer's disease: A systematic review.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016 Jan 27
Mirtazapine does not improve sleep disorders in Alzheimer's disease: results from a double-blind, placebo-controlled pilot study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022 Dec 01
Effects of quetiapine on sleep: A systematic review and meta-analysis of clinical trials.
CNS drugs, 2024 Aug 09
Effects of Trazodone on Sleep: A Systematic Review and Meta-analysis.
JAMA network open, 2020 Nov 02
Evaluation of a Patient-Centered Fall-Prevention Tool Kit to Reduce Falls and Injuries: A Nonrandomized Controlled Trial.
Age and ageing, 2022 May 01
Interventions to reduce falls in hospitals: a systematic review and meta-analysis.
Journal of advanced nursing, 2025 Feb 28
Falls in Hospitals: Challenging Traditional Risk Assessments With New Insights Into Patient Mobility.
JAMA internal medicine, 2022 Jan 01
Time to Benefit of Bisphosphonate Therapy for the Prevention of Fractures Among Postmenopausal Women With Osteoporosis: A Meta-analysis of Randomized Clinical Trials.
Annals of internal medicine, 2023 Jan 03
Effectiveness and Safety of Treatments to Prevent Fractures in People With Low Bone Mass or Primary Osteoporosis: A Living Systematic Review and Network Meta-analysis for the American College of Physicians.
Journal of oncology practice, 2017-10
REMAP: A Framework for Goals of Care Conversations.
Journal of the American Geriatrics Society, 2019 Aug 20
Swallowing Disorders in the Older Population.
Handbook of clinical neurology, 2022
Prognostication in dementia.
Journal of the American Geriatrics Society, 2014 Jul 17
American Geriatrics Society feeding tubes in advanced dementia position statement.
JAMA, 2025 Aug 12
Eating and Swallowing Problems in People With Advanced Dementia.
Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023 Sep 30
Study design and methods: U.S. study to protect brain health through lifestyle intervention to reduce risk (U.S. POINTER).
JAMA, 2025 Aug 26
Structured vs Self-Guided Multidomain Lifestyle Interventions for Global Cognitive Function: The US POINTER Randomized Clinical Trial.

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