Questions discussed in this category
E.g., amyloid PET, CSF amyloid, blood-based amyloid.
What factors might drive decisions for different SSRIs and/or doses?
For example, do you use Timed Up and Go? Chair stands? Other measures?
Would you consider adding a second medication versus uptitrating the original SSRI?
E.g., primary progressive aphasia
Are there any especially recommended screening instruments/resources?
Seminer et al., PMID 40193122
Aspirin Use to Prevent Cardiovascular Disease: Preventive Medication
Are there certain modifications to the home or aid devices that you commonly recommend? Some that are more cost-effective?
Do you ever continue medications such as rate-control agents for tachyarrhythmias, anticoagulation for blood clots, immunosuppression to prevent trans...
From a geriatrics harm-reduction standpoint, can we recommend any particulars regarding dosing or selection of therapies when used as a last resort?
There is concern for elevation in alkaline phosphatase as a precursor for bone pathology, such as an increase in risk of bone malignancy, potentially ...
O'Toole et al., PMID 36652352
If the ECG was obtained prior to major orthopedic surgery (such as hip replacement) would that change your approach?
Is this recommended TSH target of 7 or higher based on the fact that globally iatrogenic hyperthyroidism is common in older individuals on levothyroxi...
Kunadian, et al., PMID 39225274
Should some patients get 325 mg instead of 81mg at least for a certain amount of time, such as patients in the acute phase of ischemic stroke or patie...
Demay, et al., PMID 38828931
This question is part of a collaboration with RheumMadness and is specifically in reference to: NORD-STAR (Østergaard et al., PMID 3742364...
How would you work up an elderly female with persistent anemia secondary to warm AIHA requiring almost monthly transfusion, with positive ANA,dsDNA (b...
We have seen 81 vs 162 vs 325 mg up to 1300 mg.
While some have the practice of 90 days per SAMMPRIS trial, the lower rates of ischemic stroke in the medical therapy group were driven by events with...
What is the best way to treat late onset myasthenia gravis (in this case, age >90)? Would the newer complement inhibitors be safe? Steroids in this...
For example, a GAD65 Ab of 0.07 when the cut-off is 0.02. Does this answer change if you consider adult vs pediatric populations?
Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...
Small study in pediatric PACNS have evaluated this as a potential marker (Cellucci et al., PMID 22740622)
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Papers discussed in this category
Neurology, 2015-09-29
Stroke, 2017-08
Stroke, 2021 May 24
Lancet (London, England), 2014-01-25
Circulation, 2019-08-20
Archives of neurology, 2009-06
Muscle & nerve, 2013-04
Muscle & nerve, 2016-08
Muscle & nerve, 2017-07
Annals of neurology, 2017-07
Front Neurol, 2019 Jun 06
The New England journal of medicine, 2013-03-21
Neurology, 2013-08-13
The New England journal of medicine, 2017-09-14
Circ Cardiovasc Interv, 2022 Jun 23
JAMA, 2021 Dec 14
JAMA Neurol, 2020 Jul 01
JAMA Neurol, 2022 Nov 01
Circulation, 2016-11-22
JAMA, 2022 Apr 26
JAMA, 2019-02-12
JAMA, 2019-08-13
Kidney Int, 2019 Jan
Lancet (London, England), 2018-08-04
Lupus, 2024 Jan 16
Arthritis care & research, 2022 Feb 08
Journal of the Endocrine Society, 2022 Dec 02
Diagnostics (Basel, Switzerland), 2021 Apr 20
The New England journal of medicine, 2024 Sep 01
The New England journal of medicine, 2023 Jan 19
JAMA, 2022 Aug 23
Lancet (London, England), 2015 Mar 12
Journal of palliative medicine, 2012-02
Journal of the American Medical Directors Association, 2022 Mar 23
Palliative medicine, 2022 Jul
JAMA, 2021 Apr 13
Journal of the American Geriatrics Society, 2025 Jan 29
The journals of gerontology. Series A, Biological sciences and medical sciences, 2023 Jun 16
Mayo Clinic proceedings, 2000 Jan
Journal of the American Geriatrics Society, 2000 Jun
Archives of general psychiatry, 2008 Dec
Current nutrition reports, 2022 Sep 13
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2021 Feb 08
Current opinion in nephrology and hypertension, 2022 Jun 10
The Journal of clinical endocrinology and metabolism, 2022 Dec 17
J Bone Miner Res, 2024 Aug 21
J Clin Endocrinol Metab, 2023 Oct 18
Arthritis Rheumatol, 2021 Jul
Rheumatology (Oxford, England), 2023 Oct 19
Arthritis research & therapy, 2015 Aug 03
Arthritis and rheumatism, 2009 Aug
The Cochrane database of systematic reviews, 2018 Aug 23
Journal of pain and symptom management, 2018-03
Journal of general internal medicine, 2023 Oct 02
Journal of pain and symptom management, 2002-05
Annals of internal medicine, 2025 Sep 30
British journal of clinical pharmacology, 2023 Jun 13
Journal of the American Geriatrics Society, 2013 Sep
The Cochrane database of systematic reviews, 2006-07-19
Psychiatry and clinical neurosciences, 2010 Feb 01
Basic & clinical pharmacology & toxicology, 2023 Jun 20
Ochsner journal, 2013 Winter
The American journal of psychiatry, 2016-05-01
The American journal of psychiatry, 2016-05-01
JAMA, 2014 Feb 19
Frontiers in aging neuroscience, 2023 Mar 03
Journal of Alzheimer's disease : JAD, 2020
Journal of the American Geriatrics Society, 2025 Apr 28
Journal of the American Geriatrics Society, 2016 Mar 23
The Cochrane database of systematic reviews, 2018 Jun 18
The journal of nutrition, health & aging, 2008 May
The New England journal of medicine, 2022 Jul 28
Metabolism open, 2024 Jul 16
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021 May 20
Geriatric orthopaedic surgery & rehabilitation, 2011 May
Diabetes research and clinical practice, 2021 Mar 08
Journal of diabetes, 2025 Jun
Annals of internal medicine, 2021 Nov 23
JAMA, 2011-09-28
Drugs & aging, 2001
Circulation research, 2019 Mar 29
The Cochrane database of systematic reviews, 2014-03-21
Translational psychiatry, 2022 Apr 01
Journal of sleep research, 2020 Dec 02
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016 Jan 27
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022 Dec 01
CNS drugs, 2024 Aug 09