Questions discussed in this category
For what duration and is there a preferred anticoagulation agent?
Would portal hypertensive gastropathy or colopathy sway you away from using it?
IgG4 manifestations include autoimmune pancreatitis and periaortic soft tissue mass.
From NCCN (Rectal MS-33): SBRT is a reasonable option for patients who cannot be resected or ablated.
What is the role of SBRT versus microwave ablat...
Would you start with a baseline ultrasound and then pursue further workup such as fibroscan if fatty liver is present, or other?
For example, in patients who are HbSAg negative, anti-HBc positive and HbSAb negative, does vaccination reduce reactivation risk?
Or offer resection followed by adjuvant therapy?
Will the results of the recently published randomized comparison of proton beam therapy (PBT) vs. transarterial chemoembolization (TACE) change the wa...
How do you sequence systemic treatment options for in patients with Child's Pugh B (or greater) in context of IMbrave150 and HIMALAYA?
When do you in...
The patient already received PLADO+sorafenib, Y90, and Atezolizumab/Bevacizumab complicated by recurrent episodes of bleeding from esophageal varices....
Would you offer liver transplant in the setting of metastatic disease?
Would you try atezolizumab/bevacizumab or switch to a TKI?
For example in a patient with a history of PE?
i.e. EGD surveillance for varices?
ex. VEGFR2 expression, inflammatory signature, PDL1, etc.
Do you continue atezolizumab alone? Would you avoid anticoagulation?
In light of the SIRveNIB trial results and now IMbrave150, what is the role of intra-arterial therapy now?
Do you screen even asymptomatic patients?
Do you recommend TACE, RFA, radioembolization, systemic therapy or SBRT? What if the size is >5 cm?
If so, for what platelet count threshold and do you have a preference as to which agent?
Is there a "best" way to approach treatment of the viral infection i.e concurrently with therapy, prior to therapy, delayed or post therapy? Does this...
Arterial events have clear instructions to permanently discontinue on the FDA label. Especially in HCC without many other treatment options, giv...
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Papers discussed in this category
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J. Hepatol., 2016-05-01
Eur. J. Cancer, 2011-09-01
Lancet Oncol., 2015-10-01
Practical radiation oncology, 2015
Radiother Oncol, 2014 Jun
J Clin Oncol, 2013 May 1
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-02-10
Practical radiation oncology, 2015
Journal of the National Cancer Institute, 2017-09-01
Lancet (London, England), 2018-03-24
J. Hepatol., 2019 Apr 06
Gastroenterology, 2018 May 17
Clin. Gastroenterol. Hepatol., 2018 Nov 28
Hepatology (Baltimore, Md.), 2019-10
Clin. Cancer Res., 2015 Oct 23
Invest New Drugs, 2015 Apr 12
J Hepatol, 2021 May 26
N Engl J Med, 2020 May 14
NEJM Evidence, 2022 June 6
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-04-10
Cancer, 2019-09-15
Arthritis Rheumatol, 2016 Jan
Liver Cancer, 2019 Sep 18
Blood, 2020 Sep 10
Blood Adv,
The New England journal of medicine, 2018-07-05
J Gastroenterol, 2019 Nov 12
Am Heart J, 2010 Sep 18
N Engl J Med,
Lancet (London, England), 2017-01-07
The Lancet. Oncology, 2019-02
JAMA Oncol, 2020 Dec 10
Hepatology, 2019 Oct 14
Am J Transplant, 2016 Jun 09
Transplantation, 2021 Apr 27
Surgery, 2017 Jun 16
Arthritis and rheumatism, 1992-08
Arthritis and rheumatism, 1995-12
Seminars in respiratory and critical care medicine, 2002-12
Clinics in liver disease, 2019-05
Eur J Gastroenterol Hepatol,
Neth J Med,
Semin Respir Crit Care Med, 2020 Aug 10
Medizinische Klinik (Munich, Germany : 1983), 2002-11-15
Journal for scientific research. Medical sciences, 2001 Apr
Gut, 2006 May 18
Blood, 2014 Oct 15
Int J Radiat Oncol Biol Phys, 2019 Oct 1
Frontiers in oncology, 2020 Mar 24
International journal of radiation oncology, biology, physics, 2023 Apr 08
Cancer, 2023 Jul 28
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2018-03-10
N Engl J Med,
Nat Med, 2020 Apr 06
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2023 Jan 09
Cancer, 2023 Jul 06
The Lancet. Oncology, 2023 Dec 08
Cardiovascular and interventional radiology, 2023 Jul 10
The New England journal of medicine, 2021 Mar 04
Journal of thrombosis and haemostasis : JTH, 2024 Oct 21