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HLH
Questions discussed in this category
What approaches can we take to initiate therapy and improve survival rates in patients with HLH?
2 Answers available
Can a patient still have primary HLH even in the absence of any HLH associated genetic mutations?
rWGS did not demonstrate any HLH definable or associated mutations.
1 Answer available
How do you utilize cytokine panels in your clinical practice?
Is there utility when classic inflammatory markers (ESR,CRP) or disease specific markers (C3, C4, dsDNA) do not correlate with patients disease activi...
1 Answer available
How would you adjust the steroid dose for steroid-induced psychosis in a patient being treated for secondary HLH with the HLH-94 protocol?
1 Answer available
Should testing for genetic causes of HLH be performed in all patients with MAS or secondary HLH regardless of the patient's age?
2 Answers available
How do you approach dosing of anakinra in MAS?
1 Answer available
How do you approach diagnosis and treatment of HLH/MAS following CAR T-cell therapy?
How is this entity distinct from other secondary HLH entities?
2 Answers available
What is your approach to treatment of infection-triggered HLH that does not respond to treatment of the underlying infection?
2 Answers available
In the setting of secondary HLH associated with initial diagnosis of lymphoma, would you adjust steroid dose and type to account for differences in HLH and lymphoma treatment protocols?
1 Answer available
What are the best labs to trend improvement in HLH?
1 Answer available
What is the difference between Multisystem Inflammatory Syndrome in Adults (MIS-A) and MAS/HLH?
1 Answer available
How do you approach relapsed idiopathic HLH?
2 Answers available
In what circumstances would you give G-CSF to a patient with severe neutropenia and HLH?
1 Answer available
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Papers discussed in this category
Blood, 2019-06-06
Recommendations for the management of hemophagocytic lymphohistiocytosis in adults.
Eur J Haematol, 2021 Feb 17
Ruxolitinib as adjunctive therapy for secondary hemophagocytic lymphohistiocytosis: A case series.
ACR Open Rheumatol, 2021 Aug 25
Performance of Cytokine Storm Syndrome Scoring Systems in Pediatric COVID-19 and Multisystem Inflammatory Syndrome in Children.
Pediatric blood & cancer, 2011-01
Rate of decline of ferritin in patients with hemophagocytic lymphohistiocytosis as a prognostic variable for mortality.
Ther Adv Musculoskelet Dis, 2020 Nov 24
Efficacy of high-dose anakinra in refractory macrophage activation syndrome in adult-onset Still's disease: when dosage matters in overcoming secondary therapy resistance.
Frontiers in immunology, 2023 Jun 22
Approaching hemophagocytic lymphohistiocytosis.
Arthritis & rheumatology (Hoboken, N.J.), 2023 Jul 24
The 2022 EULAR/ACR Points to Consider at the Early Stages of Diagnosis and Management of Suspected Haemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome (HLH/MAS).
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