Non-melanoma skin cancer

Questions discussed in this category

Would you switch to a TNFi if a patient developed squamous cell skin cancer on abatacept after failure of methotrexate for seropositive RA?

The patient had no prior TNFi exposure and was not on methotrexate while receiving abatacept.

2 Answers available

How long can a patient with newly diagnosed merkel cell carcinoma wait for wide local excision with sentinel node biopsy?

If I can't get them in with a surgical oncologist for the lymph node would it be better to do the wide local excision in my office immediately and ris...

2 Answers available

How would you approach treatment failures with squamous cell carcinoma-keratoacanthoma-type lesions that did not respond to a standard SRT regimen after many sessions?

Have you encountered this scenario?

3 Answers available

Is the phase 2 data regarding neoadjuvant cemiplimab in cutaneous squamous cell carcinoma sufficient to adopt for all patients or will you await phase 3 data?

6 Answers available

When do you recommend SRT, if ever, for small SCCs and BCCs?

6 Answers available

Do you continue methotrexate in patients with inflammatory arthritis who develop non-melanomatous skin cancer while on therapy?

1 Answer available

Would you switch azathioprine to a different immunosuppressant if a controlled patient with SLE develops melanoma and/or non-melanoma skin cancer?

2 Answers available

For a patient treated with Mohs surgery for a high risk skin cancer of the head/neck do you post-operatively treat all scars to full dose, including those created at subsequent closure?

I have seen some patients who may undergo large complex closures (sometimes as a separate procedure) for smaller lesions with resulting scars that sig...

3 Answers available

Are you routinely using neoadjuvant cemiplimab for cutaneous squamous cell carcinoma of any site?

Majority of patients on the seminal trial (Gross et al., PMID 36094839) had tumors isolated to head & neck, what was the rationale for this?

4 Answers available

Do you consider downstaging neoadjuvant cemiplimab for borderline resectable CSCC in order to facilitate surgical resection?

3 Answers available

What role, if any, do biomarkers play in selecting appropriate patients for neoadjuvant cemiplimab in cutaneous squamous cell carcinoma?

3 Answers available

What clinical or pathologic features would make you more concerned that a new skin SCC is from metastatic disease or a new cutaneous primary?

1 Answer available

How would you approach an ulcerative non-melanomatous skin cancer of the lower extremity s/p Mohs surgery with gross disease left behind?

The lesion is still ulcerative despite wound care for two months. Would you treat immediately or wait for healing? Would hyperbaric oxygen to heal ful...

4 Answers available

How do you manage patients with erosive pustular dermatosis?

1 Answer available

How do you manage eruptive squamous atypia that does not respond to intralesional 5-fluorouracil or intralesional methotrexate?

1 Answer available

When treating with adjuvant radiation to the neck after dissection for a nodal recurrence from a nonmelanoma cutaneous malignancy, would you include the primary tumor resection bed in the field if some time has passed since the primary resection?

Would you always/never include the initial tumor bed? Is there a time interval or any other factors that would affect your management?

2 Answers available

What is the biologic of choice in a patient with RA and history of non-melanoma skin cancer?

2 Answers available

Are there guidlines for elective coverage of nodal basins in head and neck for skin cancer removed in the area?

4 Answers available

For clinically node negative large squamous cell carcinomas of the scalp vertex, would you electively treat the nodes?

If so, which levels? Bilateral? What about parotids or submandibular gland?

1 Answer available

How would you treat an unresectable SCC of the skin local recurrence in the base of skull with clinical and radiographic CN involvement?

Would you be comfortable with 55Gy in 20 fractions around the optic nerves and brainstem, or would you treat with a more protracted fractionation? Do ...

3 Answers available