What is the optimal approach for high risk prostate cancer patients who have been found to have positive nodes after surgery?
Immediate/adjuvant with 2y ADT+ARSI, or wait until PSA rise and treat as salvage. Do recent trials inform us at all about the duration of therapy, is 24 months needed (RADICALS HD), or can a shorter but intense therapy for duration of 6-9 months be considered? (FORMULA 509)