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When should SBRT be offered to oligometastatic bone disease in a patient with prostate cancer?

What factors should be considered with offering SBRT to oligometastatic bone disease in prostate cancer patients? Should this been done off of a protocol?
2 Answers
Mednet Member
Mednet Member
Radiation Oncology · Brigham and Women's Hospital
Answered on

Recently a multi-institutional analysis set standards for use in prospective assessment of SBRT for use in men with > 1 bone metastasis and up to 3 (data shown below). The Rx was well tolerated and local control was significantly improved if a BED > 100 Gy was utilized.

At this time this approach re...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Cedars-Sinai Medical Center
Answered on

SBRT for prostate cancer in the asymptomatic setting in order to improve survival or progression-free survival should be considered an unproven but potentially useful approach. Note that NRG Oncology-RTOG is testing SBRT prospectively.

Trial BR001 is a phase I trial assessing the safety of SBRT for...

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