Medical Oncology

Ovarian Cancer   

Questions discussed in this category



How does your approach vary based on residual disease left at the time of surgery? Please specify your approach for the amount of residual disease at ...

Do you prophylactically start all patients on B12, B-complex, and/or omega-3? If so, what dose? What about ice mittens and booties?

Genes such as ATM, CHEK2, PALB2, RAD51C/D, BRIP1 seem to show some potential increased risk of ovarian cancer. Should these patients under prophylacti...

s/p optimal debulking. If this was an early-stage cancer would it change your adjuvant therapy recommendations?

Recurrence picked up incidentally on CT. No germ line mutations, somatic tumor testing of node resulted negative. PET confirmed isolated recurrence

Does your practice vary based on risk status (low vs high risk) or specific mutation status (BRCA+ vs HRD+) given PAOLA subset analyses? 

What specific platforms for determining somatic BRCA and HRD status do you use for a patient who does not carry a germline BRCA mutation?

Is MDS/AML risk increased with longer duration of therapy? Does your approach differ for patients who are BRCA+/HRD vs wild type/HRP?

Given recent approval of niraparib (Zejula) for the maintenance treatment of adult patients with advanced epithelial ovarian, fallopian tube, or prima...

Does your strategy differ if the patient is on maintenance PARP inhibitor, bevacizumab, both, or neither? 

Would you approach this situation as synchronous primaries (eg. FIGO IA in both) or as a locally advanced endometrial cancer (FIGO IIIA)? What adjuva...


Papers discussed in this category


Gynecologic oncology, 2010-03

Cancer, 1987-10-15

Gynecologic oncology, 2015-09

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012-06-10

Lancet Oncol, 2017 Jun

Lancet (London, England), 2017-10-28

The New England journal of medicine, 2016-12-01

The New England journal of medicine, 2012-04-12

The Lancet. Oncology, 2017-09

J. Clin. Oncol.,

N. Engl. J. Med., 2019 Sep 28

N Engl J Med, 2019 Dec 19

The New England journal of medicine, 2011-12-29

The New England journal of medicine, 2006-01-05

Lancet Oncol, 2013 Sep

N Engl J Med, 2011 Dec 29

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-06-01

J. Clin. Oncol., 2019 Apr 19

N Engl J Med, 2016 Feb 25

The New England journal of medicine, 2018-12-27

Br. J. Cancer, 2009 Feb 17

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2011-05

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2000-01

Lancet, 2019 Nov 29

Lancet Oncol., 2014 Feb 28

Lancet,

Gynecologic oncology, 2009-08

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-04-01

Lancet Oncol.,

Br. J. Cancer, 2018 Oct 24

Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-02-15

N Engl J Med, 2019 Dec 19

J Clin Oncol, 2020 Apr 10

Lancet Oncol, 2021 Mar 18

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2019-09-10

Lancet Oncol, 2015 Jun 23

Gynecologic oncology, 2016-01

Gynecol Oncol, 2020 Jul 9

Gynecol Oncol, 2020 Jul 25

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2014-06-20

J Clin Oncol, 2020 Jul 14

J Clin Oncol, 2019 Dec 19

Ann Oncol,

JAMA oncology, 2019-03-01

N Engl J Med, 2021 Sep 18

N Engl J Med, 2022 Jan 19

The Lancet. Oncology, 2019-05

Nat Commun, 2021 May 03

Cancer medicine, 2018-06

Gynecologic oncology, 2015-03

Gynecologic oncology, 1999-02

Gynecol Oncol, 2017 May 19

N Engl J Med, 2009 Jun 10

Cancer Res, 2020 Jul 08

Gynecologic oncology, 2017-02

Lancet Oncol, 2014 Sep 28

Lancet Oncol, 2012 Nov 16

Lancet Oncol,

Gynecologic oncology, 1994-04

J Clin Oncol, 2022 Mar 20

Crit Rev Oncol Hematol, 2018 Dec 24

PLoS One, 2017 Jan 26

Gynecol Oncol Res Pract, 2018 Aug 18