Pediatric Oncology

Hemostasis/Thrombosis   

Questions discussed in this category


In the absence of concerning bleeding or thrombosis, family history of coagulopathy, current anticoagulant use, or malnutrition

I.e., what constitutes well-controlled cancer, IBD, nephrotic syndrome, etc. What other diseases do you put in this category (obesity, autoimmune dise...

How would the approach differ if the patient had a significant bleeding phenotype vs only minor bruising and mucosal bleeding?

FVL heterozygotes are often treated similarly to the general population. Aside from avoiding other VTE risk factors, are there situations where prophy...

Would you offer indefinite anticoagulation if the event is unprovoked and the patient has low bleeding risk? 

Provoked or unprovoked VTE: Do you use D-Dimer (or even repeat imaging to reassess residual clot) in any capacity to guide anticoagulation duration? E...

Have you used anticoagulants other than coumadin? Or is that the only appropriate agent given monitoring is based on PT/INR?

While this is a known risk factor for venous [Meijers et al NEJM 2000] and potentially arterial [Yang et al, Am J Clin Pathol 2006] thrombosis, it is ...

While thrombophilia testing is not routinely recommended prior to starting OCPs, how about after the development of a VTE?

Is there a preferred strategy of transfusional support versus reduced-dose anticoagulation during the duration of thrombocytopenia?


Papers discussed in this category


Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2016-04

Blood, 2018 Jul 12

Ann. Intern. Med., 2019 Oct 15

Blood Transfus, 2018 Oct 24

J Thromb Haemost, 2018 May 08

BMJ, 2008 May 20

Circulation,

Blood, 2013-12-05

Blood Adv,

Blood,

Semin Hematol,

Blood, 2016-07-14

Blood, 2016 Sep 26

Int J Lab Hematol, 2021 Oct 05