Addiction   

Questions discussed in this category



For your recommended medication, are you doing a scheduled set dose, or is it primarily symptom-driven? 

In what patient populations would you consider using disulfiram (Antabuse) instead of, or in addition to, acamprosate or naltrexone? In your experienc...

Assume QTc is not prolonged, electrolytes are reasonably normal, and the patient is not already on heavy psychotropic polypharmacy.

If so, in what settings or with which patient populations? What is the evidence for or against this treatment modality?

Do you support vaping as a harm reduction strategy? What alternatives do you recommend if patients are ambivalent about FDA-approved cessation medicat...

Is there an absolute cutoff for AST/ALT that you use where the risks outweigh the potential harm reduction benefits of using the medication? &nbs...

This is based on the recent publication by Bernstein et al., PMID 38551564 which investigated the increased rate of initiation of MAUD in the hospital...

In light of Straub et al's comparative study of combination vs buprenorphine alone

Are any effective options available beyond nicotine replacement therapy, varenicline, or bupropion?

Is there evidence for the use of varenicline, bupropion, or other medication therapies to assist in tobacco vaping cessation?


Papers discussed in this category


JAMA internal medicine, 2019 Oct 01

Frontiers in psychiatry, 2018 Oct 08

Pharmacoepidemiology and drug safety, 2018 Sep 25

The Journal of clinical psychiatry, 2020 Aug 04

The American journal on addictions, 2014

Scientific reports, 2023 Nov 28

JCI insight, 2023 Jun 22

JAMA psychiatry, 2023 Sep 01

The American journal of drug and alcohol abuse, 2023 Mar 15

Psychological medicine, 2025 Feb 12

The lancet. Psychiatry, 2019 Oct 28

Neuroscience and biobehavioral reviews, 2021 Jan 23

BMJ (Clinical research ed.), 2012 Feb 09

Journal of addiction medicine, 2021 May-Jun 01

The American journal on addictions, 2023 Mar 20

Drug and alcohol dependence, 2024 Sep 07

JAMA psychiatry, 2025 Apr 01

Journal of addiction medicine, 2020 May/Jun

Alcohol (Fayetteville, N.Y.), 2014-06

American journal of preventive medicine, 2015-10

JHEP reports : innovation in hepatology, 2024 Apr 10

JAMA, 2022 Feb 08