Questions discussed in this category
For your recommended medication, are you doing a scheduled set dose, or is it primarily symptom-driven?
In what patient populations would you consider using disulfiram (Antabuse) instead of, or in addition to, acamprosate or naltrexone? In your experienc...
Assume QTc is not prolonged, electrolytes are reasonably normal, and the patient is not already on heavy psychotropic polypharmacy.
If so, in what settings or with which patient populations? What is the evidence for or against this treatment modality?
Do you ever incorporate it into treatment, and if so, in what clinical contexts?
Do you support vaping as a harm reduction strategy? What alternatives do you recommend if patients are ambivalent about FDA-approved cessation medicat...
Is there an absolute cutoff for AST/ALT that you use where the risks outweigh the potential harm reduction benefits of using the medication? &nbs...
This is based on the recent publication by Bernstein et al., PMID 38551564 which investigated the increased rate of initiation of MAUD in the hospital...
(E.g., test taking, performance at work)
In light of Straub et al's comparative study of combination vs buprenorphine alone
Are any effective options available beyond nicotine replacement therapy, varenicline, or bupropion?
For example, related to psilocybin or synthetic THC?
What DSM-5 diagnosis and or diagnostic code do you use when treating this substance use disorder?
Is there evidence for the use of varenicline, bupropion, or other medication therapies to assist in tobacco vaping cessation?
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Papers discussed in this category
JAMA internal medicine, 2019 Oct 01
Frontiers in psychiatry, 2018 Oct 08
Pharmacoepidemiology and drug safety, 2018 Sep 25
The Journal of clinical psychiatry, 2020 Aug 04
The American journal on addictions, 2014
Scientific reports, 2023 Nov 28
JCI insight, 2023 Jun 22
JAMA psychiatry, 2023 Sep 01
The American journal of drug and alcohol abuse, 2023 Mar 15
Psychological medicine, 2025 Feb 12
The lancet. Psychiatry, 2019 Oct 28
Neuroscience and biobehavioral reviews, 2021 Jan 23
BMJ (Clinical research ed.), 2012 Feb 09
Journal of addiction medicine, 2021 May-Jun 01
The American journal on addictions, 2023 Mar 20
Drug and alcohol dependence, 2024 Sep 07
JAMA psychiatry, 2025 Apr 01
Journal of addiction medicine, 2020 May/Jun
Alcohol (Fayetteville, N.Y.), 2014-06
American journal of preventive medicine, 2015-10
JHEP reports : innovation in hepatology, 2024 Apr 10
JAMA, 2022 Feb 08