Medical Oncology

EGFR+   

Questions discussed in this category



Would you offer adjuvant atezolizumab, osimertinib, or neither? Both IMpower010 and ADAURA only had patients with EGFR exon 19 deletion or L858R mutat...

How do you balance the risk of an EGFR flare while holding osimertinib vs the risk of pneumonitis when continuing?

Are there specific mutations or co-mutations were you would consider use of this agent? 

1st-line pembrolizumab is supposed to be used AFTER failure of appropriate targeted agents in this setting, but would you consider the reverse sequenc...


Papers discussed in this category


The New England journal of medicine, 2015-10-22

The New England journal of medicine, 2016-11-10

J Thorac Oncol,

Clin. Cancer Res., 2015 May 27

Lancet (London, England), 2017-01-21

Lancet (London, England), 2016-04-09

The New England journal of medicine, 2018-06-14

The Lancet. Respiratory medicine, 2019-05

Ann. Oncol.,

The New England journal of medicine, 2018-12-13

J. Clin. Oncol., 2019 Dec 11

Lancet Oncol., 2017 Sep 25

N Engl J Med, 2020 Sep 19

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-12-01

J Clin Oncol, 2020 Dec 04

Clin Oncol (R Coll Radiol), 2017 Nov 16

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2014-06

Radiother Oncol, 2020 Jul 31

The Lancet. Oncology, 2015-07

Annals of oncology : official journal of the European Society for Medical Oncology, 2019-08-01

J BUON,

Br J Cancer, 2019 Sep 30

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2013-01

Future Oncol, 2018 Nov 08

World J Clin Cases,

Br J Cancer, 2016 Nov 22

Biochemistry, 2015 Jul 06

N Engl J Med, 2019 Nov 21

Lancet Oncol, 2016 Apr 12

Clinical cancer research : an official journal of the American Association for Cancer Research, 2011-10-01

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2015-01

Lung Cancer, 2020 Nov 13

Neuropathology, 2019 Mar 13

Respir Investig, 2014 Nov 13

JACC CardioOncol, 2019 Dec 17

J. Clin. Oncol., 2008-07-20

J Clin Oncol, 2021 Nov 02

Lancet, 2021 Sep 20

FEBS J, 2009 Nov 18

Clin Lung Cancer, 2018 May 01

J Thorac Oncol, 2021 Feb 01