Adverse Events

Questions discussed in this category

When, if ever, do you incorporate a dental evaluation before initiating Dato-DXd to offer guidance on oral care and help limit oral toxicity?

How should this differ from evaluations done for bisphosphonates/denosumab, for example?

2 Answers available

How does your management of stomatitis from Dato-DXd compare to your approach for stomatitis from other cancer-directed treatments?

3 Answers available

What strategies can we use to help patients receiving Dato-DXd report symptoms earlier, with the goal of early intervention to prevent progression to higher grade side effects?

3 Answers available

How should Dato-DXd be managed in the absence of necessary resources for ocular exams and referrals?

What is the ideal timing and frequency of referrals for exams? What is the bare minimum if access is limited?

3 Answers available

What is typical presentation and time course for belimumab infusion-related depression and/or hallucinations, and how do you approach management?

1 Answer available

Do you recommend Hyaluronic Acid Therapy for vaginal dryness in female patients post pelvic RT?

How do you incorporate this into your follow-up care and how do you instruct the patient?

2 Answers available

How do you treat severe vaginal stenosis after radiation in a patient that is already compliant with dilators?

2 Answers available

How do you manage internal vaginal burning during pelvic radiation?

Are there any creams or suppositories that can be safely applied internally in the vagina to soothe burning?

1 Answer available

Would you give pentoxiphylline and vitamin E during HBO for vaginal necrosis?

1 Answer available

Is there an effective treatment for severe radiation fibrosis of the skin after radiotherapy to the breast or other areas?

I have heard of long-term pentoxifylline and Vitamin E daily combination that can prevent and even reverse radiation fibrosis (Delanian et al., PMID 1...

5 Answers available

How do you advise patients on the risk for permanent alopecia following RT to the scalp?

In treating skin cancers of the scalp, are there any specific constraints you give to the skin itself to prevent alopecia? How does changi...

2 Answers available

When would you recommend hyperbaric oxygen treatments for skin ulceration/non-healing wounds in a radiated field?

2 Answers available

Is it safe to give thoracic irradiation to a patient with lung cancer previously treated with a VEGF inhibitor?

I've read about patients who were treated with concurrent bevacizumab-RT who developed lethal tracheoesophageal fistulas. How long would you have to w...

1 Answer available