Sickle Cell   

Questions discussed in this category


If hydroxyurea modifies the course of sickle cell disease by increasing fetal hemoglobin, is there any benefit to using it in patients with fetal hemo...

While L-glutamine has minimal side effects and would likely be added after hydrea, how do you decide between the use of voxelotor and crizanlizumab?

Also is there value in using voxelotor for the purpose of reducing hemolysis, and if so what parameters do you use to determine when to initiate voxel...

Hydroxyurea is demonstrated to reduce complications and improve long-term outcomes in severe genotypes HbSS and sickle beta0 thalassemia. What clinica...

While building a trusting patient-physician relationship, what therapies could be discussed that may be aligned with naturopathic medicine? (i.e. L-gl...

What are your target goals during transfusion, either prophylactically or during acute complication? Does your management change between vaginal deliv...

Has your medical practice taken any steps either in community outreach or within the clinic to show support for this medically vulnerable population, ...

What is the lowest level you have seen with uncomplicated or complicated crises?


Papers discussed in this category


Blood, 2015-05-28

Blood Adv, 2020 Jan 28

Blood, 2015 Aug 24

The New England journal of medicine, 2017-02-02

Blood, 2009 Nov 10

N Engl J Med,

Am J Prev Med,

J Natl Med Assoc,

J Adv Nurs, 2015 Sep 09

Issues Ment Health Nurs, 2018 Apr 13

JAMA Netw Open, 2020 May 01

Emerg Infect Dis, 2020 Jul 08

Transfus Med Rev,

Blood, 2010-11-04

Pediatric blood & cancer, 2014-05

British journal of haematology, 2015-05

Oman Med J, 2020 Nov 07

Pediatr Blood Cancer, 2020 Sep 08

Blood Adv,

Hemoglobin, 2021 May 24

Transfusion, 2020 Sep 24

Lancet (London, England), 2016-02-13

Transfusion, 2017 May 03

Blood, 2019 Apr 25

J Clin Med, 2020 Nov 23

Am J Hematol, 2012 May 28

Journal of the National Medical Association, 2009-10

Blood,