Psychiatry

Psychopharmacology

Questions discussed in this category

When do you recommend HLA testing prior to prescribing lamotrigine, carbamazepine, or oxcarbazepine to patients of Asian descent?

3 Answers available

What is your approach to using newer atypical antipsychotics in the treatment of schizophrenia?

E.g., Latuda (lurasidone), Fanapt (iloperidone), Vraylar (cariprazine), Rexulti (brexpiprazole), Caplyta (lumateperone), or Saphris (asenapine), Lybal...

3 Answers available

What is your pharmacological approach to treating depressive disorders in patients who develop serotonin toxicity?

How does the development of serotonin toxicity/syndrome change your usage of serotonergic medications? Which medications/classes of medications do you...

1 Answer available

What is your experience in the efficacy of vortioxetine for treating anxiety disorders?

1 Answer available

How do you use lithium levels to adjust treatment during mania?

2 Answers available

When is the best time to get a valproate level if a patient is taking Depakote DR once daily?

3 Answers available

What treatment and management recommendations do you have for amphetamine-induced skin picking disorder without insight?

5 Answers available

When do you consider using Uzedy, the subcutaneous long-acting injectable version of risperidone?

1 Answer available

How do you decide which commercially available pharmacogenetic test to use for your patients?

Are there specific testing companies you prefer? How do you weigh the differences between options such as GeneSight and Genomind? In what situations w...

2 Answers available

How do you manage polyuria and polydipsia from lithium?

2 Answers available

How do you counsel/approach antidepressant use in patients planning to utilize or self-administer psychedelics for chronic PTSD or depression?

With patients increasingly accessing psychedelics through online forums or home-grown sources for chronic PTSD and depression, how should psychiatrist...

1 Answer available

How do you view the risk of tardive dysinesia and other side effects in your female patients with treatment-resistant depression who are stable on an atypical antipsychotic?

Given the concern about potential TD in female patients treated with second-generation atypical antipsychotics as an adjunct to antidepressants, are y...

5 Answers available

What is your approach to delayed or inhibited ejaculation related to SSRI sexual dysfunction?

What are other ways to treat this beyond reducing the dose / switching medications? What interventions have you had the most success with?

1 Answer available

Would you consider prescribing NAC for a patient with OCD and a documented sulfa allergy?

2 Answers available

How do you approach diagnosing suspected early tardive dyskinesia with minimal positive findings on AIMS examination?

1 Answer available

How do you approach agitation management, especially the use of neuroleptics in hospitalized patients with a prolonged QTc?

2 Answers available

How do you monitor patients who are symptomatically well-managed on clozapine with supratherapeutic drug levels?

2 Answers available

When do you consider pharmacogenetic testing to assist in the selection of antipsychotic medications?

In light of publication from Gras et al., PMID 40662264

1 Answer available

How do you manage nausea side effects in patients on cariprazine?

1 Answer available

How do you approach prescribing oxcarbazepine when the patient is on an oral contraceptive?

1 Answer available

When do you attribute tremors to lamotrigine?

3 Answers available

How do you decide between initiating antidepressants vs. hormone replacement therapy for post-menopausal depression?

2 Answers available

What types of cardiac conduction abnormalities would lead you to avoid using tricyclic antidepressants?

8 Answers available

Would you recommend CRRT instead of intermittent hemodialysis to prevent lithium rebound in a patient with lithium toxicity after an initial intermittent hemodialysis session?

4 Answers available

How do you manage withdrawal symptoms of SNRIs that exist even after slow taper?

2 Answers available

How will the removal of the clozapine REMS requirement change your clinical practice?

4 Answers available

When do you consider adding an antipsychotic for SSRI-refractory OCD, and which agent do you typically choose first?

2 Answers available

When do you consider antipsychotic augmentation of antidepressants for PTSD?

In light of publication from Davis et al., PMID 39693081.

1 Answer available

Would you consider changing management for a patient with bipolar disorder stable on an antipsychotic who is on anticoagulation after a recent PE or VTE?

How strong is the evidence that antipsychotic medication can increase the risk of venous thromboembolism and pulmonary embolus?

1 Answer available

Have you observed adverse mental health side effects in patients who start montelukast?

In light of the FDA warning about mental health side effects of the medication have you observed in particular any patients develop suicidal thoughts ...

6 Answers available

Do you tend to avoid the use of oral weight loss stimulant medications such as phentermine in obese patients on SSRI or ADHD treatments?

1 Answer available

How do you manage emotional blunting due to SSRIs/SNRIs?

7 Answers available

How do you approach titration or transitioning to Cobenfy in patients currently on an antipsychotic?

1 Answer available

In your experience how does the dose of Remeron (mirtazapine) influence side effects like hunger and weight gain?

3 Answers available

What are your preferred methods for QTc calculation for normal, tachycardic and bradycardic heart rates?

1 Answer available

How do you cross-taper when switching from an SSRI to an SNRI?

2 Answers available

How frequently do you recommend EKGs in pediatric patients on antipsychotics, especially in patients taking antipsychotics with more QTc risk?

1 Answer available

What parameters do you follow to avoid rebound effects when using clonidine only for nightly or daily as-needed indications?

1 Answer available

Papers discussed in this category

CNS drugs, 2022 Jun 27

A Guideline and Checklist for Initiating and Managing Clozapine Treatment in Patients with Treatment-Resistant Schizophrenia.

Therapeutic drug monitoring, 2006 Jun

Does it really matter when a blood sample for valproic acid concentration is taken following once-daily administration of divalproex-ER?

JAMA psychiatry, 2020 Mar 01

Effects of Mirtazapine for Methamphetamine Use Disorder Among Cisgender Men and Transgender Women Who Have Sex With Men: A Placebo-Controlled Randomized Clinical Trial.

The American journal of psychiatry, 2023 Feb 22

Double-Blind Placebo-Controlled Study of Memantine in Trichotillomania and Skin-Picking Disorder.

JAMA psychiatry, 2025 Mar 01

Brexpiprazole and Sertraline Combination Treatment in Posttraumatic Stress Disorder: A Phase 3 Randomized Clinical Trial.

The American journal of psychiatry, 1973 May

The 24-hour serum lithium level as a prognosticator of dosage requirements.

British journal of pharmacology, 2021 May 05

N-acetylcysteine as a new prominent approach for treating psychiatric disorders.

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