Radiation Oncology

Small cell lung cancer   

Questions discussed in this category


This has become standard practice at our institution for patients with a good performance status, with whole brain radiotherapy given after the comple...

Would you consider it for a patient who had bulky thoracic disease, only a single extrathoracic site of involvement and achieved a CR after induction ...

If yes, do you recommend it be given concurrently with chemotherapy or sequentially? What is your target volume and dose?

Would you treat the nodes with margin, the nodal group, or the whole untreated mediastinum?

If you are using a standard 30/10 fractionation, is there a benefit to keeping chemo on board for radio-sensitization?

As a for instance, a centrally located primary tumor with mediastinal adenopathy that results in a TE fistula? Currently we would recommend esophagea...

Does it factor into your decision making in the setting of restricted spirometry and normal lung volumes? Does this differ for SBRT v. chemoRT?

If a patient clearly has N1 disease with high SUV on PET, do you routinely recommend EBUS or mediastinoscopy to evaluate for N2 disease?

Would you repeat PET or is it adequate to change to CT surveillance? Although surveillance PET/CT is not recommended by NCCN guidelines, these are oft...

Or would you wait to start coincident with the start of cycle 2? If a shorter time from the start of any therapy to the end of radiation (SER) is sign...

In a patient with newly diagnosed small cell lung cancer with disease limited only to the thorax would you treat with definitive chemoRT in the presen...


Papers discussed in this category


N Engl J Med, 2007 Aug 16

J Clin Oncol, 1999 Jul

Lancet, 2015 Jan 3

International journal of radiation oncology, biology, physics, 2011-11-01

Int. J. Radiat. Oncol. Biol. Phys., 2006-09-01

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2017-12

Lancet Oncol., 2017-05-01

The New England journal of medicine, 1999-08-12

BMC Cancer, 2015-08-15

Journal of cancer research and therapeutics, 2012

International journal of radiation oncology, biology, physics, 2012-05-01

Neurosurgery, 2013-10

Practical radiation oncology, 2015

J. Neurosurg., 2005-01-01

J Korean Neurosurg Soc, 2011-08-01

Radiat Oncol, 2014-07-08

BMC Cancer, 2015-03-04

Acta Neurochir (Wien), 2013-01-01

JAMA, 2016-07-26

Radiation oncology (London, England), 2014-09-30

Cancer, 2016-06-15

The New England journal of medicine, 2018-12-06

Lancet, 2019 Oct 04

J Clin Oncol, 2020 Aug 10

Lung Cancer, 2014 Aug 02

N Engl J Med,

Lancet Oncol, 2020 Apr 03

N. Engl. J. Med., 1999-01-28

J Thorac Oncol,

Int. J. Radiat. Oncol. Biol. Phys., 2010-06-01

International journal of radiation oncology, biology, physics, 2013-03-01

Respir. Res., 2018 Apr 24

International journal of radiation oncology, biology, physics, 2011-10-01

International journal of radiation oncology, biology, physics, 2012-06-01

Int. J. Radiat. Oncol. Biol. Phys., 2008 Jan 30

Thorac Surg Clin,

N Engl J Med, 2017 Nov 16

The Lancet. Oncology, 2009-05

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2019-02