Liver and Pancreas Tumors
Questions discussed in this category
When using hypofractionated RT (i.e., 67.5 Gy in 15 fractions), can chemotherapy be delivered concurrently?
Options for systemic therapy in NCC...
Plan to give adjuvant chemotherapy.
Should Y90 be offered before or after TACE (based on the Northwestern phase 2 study) or sorafenib (based on the SARAH trial)?
I can't convince the surgeons to refer their patients for adjuvant RT because the prospective data is messy and doesn’t seem to indicate a benef...
Please specify how your institution is allocating resources now or will be soon.
What were your “top 3” presentations/studies coming out of the meeting this year and how will it impact your own clinical practice?
...
If borderline resectable, can the TOPAZ regimen be considered for downstaging effects?
If multi-agent systemic therapy, i.e. FOLFIRINOX, is also planned, is there a preferred sequence of therapies?
Colloid is a rare histologic subtype and considered to have more favorable outcomes compared with usual ductal adenocarcinoma, but no dedicated prospe...
Would you recommend radiation, systemic therapy alone, or chemoRT? What about if this recurrence occurred during or shortly after completion of adjuva...
Do you continue atezolizumab alone? Would you avoid anticoagulation?
In light of the SIRveNIB trial results and now IMbrave150, what is the role of intra-arterial therapy now?
Is there evidence for radiation therapy in this setting?
Is there a "best" way to approach treatment of the viral infection i.e concurrently with therapy, prior to therapy, delayed or post therapy? Does this...
Would you alter your SBRT dose? How long would you hold the VEGF inhibitor before and after? Does the primary matter (e.g. NSCLC vs. colorectal)?
What are the targets (tumor bed, positive margin, nodes etc.)?
Is there a role for SBRT with or without the addition of systemic therapy?
What features would make you more likely to recommend radiation therapy with chemotherapy?
Have you ever seen toxicity related to diaphragm dose with conventional fractionation?
How would the new data presented at ASCO GI 2021 from from Alliance A021501 influence your answer?
When planning SBRT cases for primary liver cancers, it is very difficult to see the tumor on the non-contrast 4D scan. How do you use information from...
For cases with positive margins, do you boost to 54 Gy? If so, do you boost the entire tumor bed or only the area of the positive margin?
I recently had a patient with unresectable disease ask for a PET before starting RT but I’m not sure there is a benefit.
What techniques work best?
19600572119691660529516380159001534214616119551153911925101776362962682598183816073715159606858695682623476550805004369345921899714931818294296
Papers discussed in this category
Cancer, 2007-11-15
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-07-20
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008-07-20
Cancer, 1987 Jun 15
Ann Surg, 2007 Nov
Cancer, 2015-04-01
JAMA, 2012 Jul 11
JAMA, 2008-03-05
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011-08-01
International journal of radiation oncology, biology, physics, 2011-09-01
American journal of clinical oncology, 2011-02
International journal of radiation oncology, biology, physics, 2013-12-01
JAMA, 2007 Jan 17
Lancet Oncol., 2017 Oct 26
Cancer medicine, 2022 Aug 09
J. Clin. Oncol., 2020 Feb 27
Cancer, 2011-09-01
International journal of radiation oncology, biology, physics, 2015-07-01
Cancer treatment reviews, 2017-02
Strahlenther Onkol, 2019 Feb 08
Radiother Oncol, 2018 Jul 09
J. Hepatol., 2019 Apr 06
International journal of radiation oncology, biology, physics, 2016-03-15
Cancer medicine, 2019-05
American journal of clinical oncology, 2019-03
N Engl J Med, 2020 May 14
Liver Cancer, 2019 Sep 18
Hepatology (Baltimore, Md.), 2018-08
Radiology, 2018-06
Hepatology, 2021 Mar 19
The Lancet. Oncology, 2013-04
Ann Surg,
Int J Radiat Oncol Biol Phys, 2021 Aug 01
J Clin Oncol, 2022 Jan 27
N. Engl. J. Med.,
JAMA oncology, 2019-06-01
Transpl Int, 2010 May 20
NEJM Evidence, 2022 Jun 1
Eur J Surg Oncol,
World J Surg, 2019 Apr
J Surg Oncol, 2020 Sep 24
World J Gastrointest Surg, 2019 Jun 27
The New England journal of medicine, 2013-10-31
N. Engl. J. Med.,
Lancet, 2021 Jun 05
Eur J Cancer, 2018 Aug 24
Journal of the National Cancer Institute, 2016-06
Pediatrics, 2014 Feb 02
N. Engl. J. Med.,
The Journal of urology, 2018-12
Lancet Oncol., 2014 Feb 18
Br J Cancer, 2014 Apr 15
Cancer, 2011-06-15
Eur J Cancer, 2017 Nov 28
N. Engl. J. Med., 2019 Sep 28
Lancet Oncol, 2021 Jan 18
J Clin Oncol, 2021 Apr 19
J Clin Oncol, 2003 Jul 01
N Engl J Med, 2023 Jun 04
Lancet Oncol, 2021 May 04
Lancet Oncol, 2023 Jun 02
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-01-20
Pract Radiat Oncol, 2021 Oct 21
Lancet (London, England), 2023 Apr 16
NEJM evidence, 2022 Jun 01