Hepatocellular Carcinoma   

Questions discussed in this category


Are there factors which would make you more likely to use atezo/bev vs durva/treme vs TKI?

Would portal hypertensive gastropathy or colopathy sway you away from using it?

Will the results of the recently published randomized comparison of proton beam therapy (PBT) vs. transarterial chemoembolization (TACE) change the wa...

What if actively on immunosuppression or with active lupus? For this case, presume the patient is not a candidate for resection or IR guided therapies...

What were your “top 3” presentations/studies coming out of the meeting this year and how will it impact your own clinical practice? ...

Is there a difference in efficacy if dose is given later point during the course of therapy?

How do you sequence systemic treatment options for in patients with Child's Pugh B (or greater) in context of IMbrave150 and HIMALAYA? When do you in...

The patient already received PLADO+sorafenib, Y90, and Atezolizumab/Bevacizumab complicated by recurrent episodes of bleeding from esophageal varices....

Would you offer liver transplant in the setting of metastatic disease? 

What parameters do you use to decide to treat beyond progression? Is there any efficacy data from this specific study subgroup in IMbrave150?

In light of the SIRveNIB trial results and now IMbrave150, what is the role of intra-arterial therapy now?


Papers discussed in this category


Clin. Cancer Res., 2015 Oct 23

Invest New Drugs, 2015 Apr 12

J Hepatol, 2021 May 26

N Engl J Med, 2020 May 14

NEJM Evidence, 2022 June 6

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-04-10

Cancer, 2019-09-15

Liver Cancer, 2019 Sep 18

The New England journal of medicine, 2018-07-05

Lancet (London, England), 2018-03-24

J Gastroenterol, 2019 Nov 12

Am Heart J, 2010 Sep 18

N Engl J Med,

Lancet (London, England), 2017-01-07

The Lancet. Oncology, 2019-02

JAMA Oncol, 2020 Dec 10

Hepatology, 2019 Oct 14

Annals of oncology : official journal of the European Society for Medical Oncology, 2024 Feb 19

Br J Cancer, 2021 Feb 03

Hepatogastroenterology, 2013 Jan 16

Medicine (Baltimore),

Cancers (Basel), 2022 Mar 28

The New England journal of medicine, 2013-10-31

N. Engl. J. Med.,

Lancet, 2021 Jun 05

Eur J Cancer, 2018 Aug 24

NEJM Evidence, 2022 Jun 1

International journal of radiation oncology, biology, physics, 2008-06-01

International journal of radiation oncology, biology, physics, 1989-10

JAMA Netw Open, 2021 Feb 01

Future Oncol, 2020 Apr 30

N Engl J Med, 2023 Jun 04

Lancet Oncol, 2021 May 04

Lancet Oncol, 2023 Jun 02

NEJM evidence, 2022 Jun 06

Int J Radiat Oncol Biol Phys, 2019 Oct 1

Frontiers in oncology, 2020 Mar 24

International journal of radiation oncology, biology, physics, 2023 Apr 08

Cancer, 2023 Jul 28