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Transplant Infectious Disease   

Questions discussed in this category

How long do you treat uncomplicated gram-negative rod bacteremia in solid organ transplant recipients?
1 Answer available
Would you consider antifungal prophylaxis for immunocompromised patients with COVID-19 requiring mechanical ventilation, considering the high risk of invasive pulmonary aspergillosis in patients with severe COVID-19?
Feys et al., PMID 37691392 
1 Answer available
What is your preferred agent for fungal prophylaxis in a patient post lung transplant with abnormal LFTs?
Do you consider isavuconazole to be less hepatotoxic than other azoles?
2 Answers available
Are there instances when you use letermovir without the addition of acyclovir when managing a kidney transplant recipient for CMV prophylaxis?
3 Answers available
Do you manage antibacterials for enterococcal bacteremia differently in patients with severe immunosuppression?
2 Answers available
Would you recommend imaging of the brain and lungs to investigate potential disseminated disease in a recent heart transplant patient with a skin nodule that grew Rhizopus?
1 Answer available
How would you manage persistent Norovirus diarrheal infections in a kidney transplant patient that are not responding to a decrease in the patient’s maintenance immunosuppressive regimen?
3 Answers available
Do you treat non-albicans strains of Candida on sputum culture or BAL in patients who are immunosuppressed?
2 Answers available
What is your preferred dosing of IV ganciclovir for CMV disease in immunocompromised patients?
1 Answer available
What are your top takeaways from ID Week 2024?
1 Answer available
Would you transition from IV to oral antibiotics in a solid organ transplant recipient with uncomplicated gram-negative bacteremia?
Nussbaum et al., PMID 38195100
1 Answer available
Is there a role for nitazoxanide for treatment of norovirus gastroenteritis in immunocompromised patients?
1 Answer available
Under which circumstances is there a role for reduction in immunosuppression post-SOT in a patient with recurrent CMV viremia and/or disease? 
1 Answer available
What is your approach to antimicrobial prophylaxis in adult patients undergoing treatment for HLH?
1 Answer available
Is there a role for secondary CMV prophylaxis in solid organ transplant patients?
1 Answer available
What is current best practice with regards to antibacterial prophylaxis in patients with hematologic malignancy and resolved neutropenic fever (>72 hours)?
1 Answer available
What is your approach to vaccinations and titers for patients with myeloma, who are immunosuppressed and do not have appropriate antibody responses to vaccines?
E.g., for a patient with myeloma, s/p induction therapy, and high-dose chemotherapy, followed by autologous rescue with inappropriate antibody respons...
3 Answers available
Is there ever a role for the use of CMV immune globulin for treatment of CMV viremia and/or disease?
1 Answer available
Do you use letermovir as CMV prophylaxis in solid organ transplant patients?
1 Answer available


Papers discussed in this category

Curr Opin Infect Dis, 2023 Aug 1
Neutropenia and antibiotics: when, what, how and why?
JAMA, 2023 Jul 03
Letermovir vs Valganciclovir for Prophylaxis of Cytomegalovirus in High-Risk Kidney Transplant Recipients: A Randomized Clinical Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2017-11-29
Role of Secondary Prophylaxis With Valganciclovir in the Prevention of Recurrent Cytomegalovirus Disease in Solid Organ Transplant Recipients.
Annual review of medicine, 2022 Nov 04
Cytomegalovirus Therapy: Role of Letermovir in Prophylaxis and Treatment in Transplant Recipients.
The Journal of infection, 2011-11
Norovirus gastroenteritis successfully treated with nitazoxanide.
Alimentary pharmacology & therapeutics, 2006 Nov 15
Nitazoxanide in the treatment of viral gastroenteritis: a randomized double-blind placebo-controlled clinical trial.
Journal of tropical medicine, 2017 Feb 26
Nitazoxanide in Acute Rotavirus Diarrhea: A Randomized Control Trial from a Developing Country.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024 Jul 19
Oral Antibiotics for Treatment of Gram-Negative Bacteremia in Solid Organ Transplant Recipients: A Propensity Score Weighted Retrospective Observational Study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020 Nov 05
Orally Administered Human Immunoglobulin Therapy for Norovirus Enteritis in Solid Organ Transplant Recipients: A Case Series at a Single Academic Transplant Center.
Clinical transplantation, 2022 Jan 20
Nitazoxanide treatment for norovirus infection in solid organ transplant recipients.

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