Endocrinology

Thyroid Disorders   

Questions discussed in this category



There is literature showing small changes in both free T4 and TSH (despite steady state) in the first few hours after ingestion of L-T4. In occasional...

Patient had intolerance to methimazole and then developed agranulocytosis with PTU. FT4 is 2.9 (upper normal range is 1.7). I have started the patient...

Female is in her later 40s with surgical oophorectomy taking Sertraline 50 mg daily and prn Trazodone and Lamotrigine. Has some weight loss and fatigu...

Elderly male with primary hypothyroidism, HTN, and progressive worsening cognition over several months. PCP has been increasing LT4 dose as outpatient...


Papers discussed in this category


The New England journal of medicine, 2019 Mar 23

BMC medicine, 2019-07-10

JAMA, 2017 Dec 12

The lancet. Diabetes & endocrinology, 2022 Mar 14

The New England journal of medicine, 1980-04-17

International journal of endocrinology, 2015 Oct 20