NCI-CCC Lymphoma Tumor Board Question
Questions discussed in this category
At the time of initial diagnosis, there was no clear CNS involvement. When it became clinically apparent disease was refractory to EPOCH, there was CS...
DLCO 65% that is of unclear etiology but not due to disease and no cardiac or pulmonary functional limitations.
Would you continue R-CHOP or would you switch therapy?
Would you consider this de novo DLBCL (unable to assess for clonality)? How would you handle prior anthracycline exposure?
Specifically, in the setting of patients that have had a PR or VGPR and are not actively progressing.
240-300 mg/m2 prior exposure. How would your management change in young fit/older individuals with comorbidities? Would you obtain interval TTE during...
Would your approach differ for a 30 year old and a 70 year old?
Do you incorporate PEG-asparaginase or brentuximab vedotin (for CD30-expressing malignant cells) into anthracycline-based induction regimens? Do you c...
How do you choose between CAR-T and autoSCT, for example?
Would you still go to auto or consider allo?
Would you intercalate HD-MTX with her CHOEP?
Would you give R-CHOP without knowing if there was use of prior anthracycline?
Ki67 = 90% with multiple small nodes on PET scan and normal CBC
Patient in mid-30s with no major medical history presented with isolated left neck swelling. Incisional biopsy w/ HTLV1/2 associated ATLL, Ki67 of >...
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Papers discussed in this category
Eur J Haematol, 2023 Mar 27
Haematologica, 2021 Jun 01
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2009-03-10
The New England journal of medicine, 2015-11-05
Haematologica, 2018 May 24
Blood,
Leukemia, 2011 Jul 01
Haematologica, 2019 Sep 19
Blood, 2017 Aug 17
Blood, 2015 May 28
British journal of haematology, 2017-11
J Clin Oncol, 2016 Feb 29
Lancet Haematol, 2016 Dec 05
Lancet Oncol, 2022 Jan 21
N Engl J Med,
Lancet (London, England), 2019-01-19
N Engl J Med, 2022 Dec 11
J Clin Oncol, 2022 Dec 22
Blood Adv, 2022 May 10
Blood, 2022 Dec 15
J Clin Oncol, 2021 Jun 25
Annals of oncology : official journal of the European Society for Medical Oncology, 1993-11
Ann Oncol, 2009 Jul 01
Blood, 2010 Jul 21
Blood, 2022 Mar 03
Lancet,
N Engl J Med, 2021 Dec 11
Cancer cell, 2017-06-12
J Neurooncol, 2022 Jun 20
Lancet Oncol, 2020 Jun 05
Lancet Oncol, 2022 Jul 12
J Clin Oncol, 2017 Jan 17
The Lancet. Oncology, 2011 Dec 13
American journal of hematology, 2022 Jul 05
Blood advances, 2023 Oct 24
Blood, 2018 Aug 14
American journal of hematology, 2016-09
Blood, 2017 Jun 13
JAMA, 2023 Aug 8
Blood, 2017 Jan 31
Blood, 2020 Apr 09
Blood advances, 2023 Sep 26