Questions discussed in this category

Do you treat with only an IV steroid pulse or do you use an oral steroid taper as well? How long of a taper do you typically use?

In addition, what formula do you use to calculate the IgG index?

Anecdotally, the diagnostic yield in these patients seems quite low, yet autoimmune encephalitis is often invoked in such patients, particularly in th...

If a patient has classic TM symptoms but a normal MRI, are there specific causes you look for?

Do you just use antibiotic prophylaxis if therapy is started prior to meningococcal vaccination?

Based on this review (Melamed and Lee, PMID 31998289), patients with MS on several DMTs may be at higher risk for certain cancers. How does this play ...

Instead of waiting for the antibody test to result, if you have a high suspicion for NMDAR encephalitis, is there a role for giving rituximab alongsid...

Do you wait for a second clinical event or start immunomodulatory therapy right away?

Specifically, what do you do if there is minimal improvement with IV steroids and/or IVIG?

Are there any specific patient populations that you are no longer routinely recommending to start B-cell depleting medications? For example, are you l...

Based on the results of the recent longitudinal analysis linking EBV infection and MS (Bjornevik et al., PMID 35025605), can negative EBV antibodies (...

Small study in pediatric PACNS have evaluated this as a potential marker (Cellucci et al., PMID 22740622)

Do you approach things differently if a rare variant like this is suspected? Is the Balo's subtype more similar to RRMS or PPMS?

Papers discussed in this category

Mult Scler, 2018 Feb

Neurology, 2020 Jul 29

Cells, 2018 Dec 28

Neurol Sci, 2015 Jun 25

World J Clin Cases,

Mult Scler Relat Disord, 2020 Dec 16

Archives of neurology, 2009-06

Muscle & nerve, 2013-04

Muscle & nerve, 2016-08

Muscle & nerve, 2017-07

Annals of neurology, 2017-07

Front Neurol, 2019 Jun 06

Neurology(R) neuroimmunology & neuroinflammation, 2017-07

J Med Life,

J Clin Neurol, 2018 Feb 28

Mult Scler, 2014 Mar 03

Mult Scler Relat Disord, 2016 Dec 23

N Engl J Med,

Lancet, 2016 Mar 04

Arthritis Rheum,

Journal of neurovirology, 2018-06

The Lancet. Neurology, 2013-06

Neurologic clinics, 2008-08

Neuroepidemiology, 2007 Sep 11

The Lancet. Neurology, 2014-02

The New England journal of medicine, 2017-01-19

N Engl J Med,

J Allergy Clin Immunol, 2022 Feb 14

Mult Scler Relat Disord, 2021 Sep 04

Muscle & nerve, 2007-01

Annals of neurology, 1990-03

Rheum Dis Clin North Am, 2017 Aug 23


Medicine (Baltimore),

Muscle Nerve, 2014 Dec 23

Archives of ophthalmology (Chicago, Ill. : 1960), 1988-08

Neurology, 2011-01-18

The Lancet. Neurology, 2016-04

Lancet Neurol, 2020 Nov 23

Clin Microbiol Infect, 2018 Feb 07

Neurology, 2021 Oct 05

Neurology, 2017-11-14

Neurol Neuroimmunol Neuroinflamm, 2020 Jul 27

Arthritis and rheumatism, 2009-11

Rheumatology (Oxford), 2014 Oct 21

Cureus, 2019 Aug 19

J Rheumatol, 2007 Sep 15

Rheumatol Int, 2007 Jul 20

Lupus, 2017 Feb 26