Bone and Calcium Disorders
Questions discussed in this category
Do anabolic agents have a role?
With the time intervals recommended after taking each medicine, I am wondering how patients should be counseled.
Is this seen more with high dose vitamin D supplementation?
Normal Vitamin D, bone scan showed osteoarthritis
Do treatments for osteoporosis have a large enough effect on tooth movement to make Invisalign less effective?
Can 25 OH vitamin D be converted to activated vitamin D outside of PTH mediated mechanisms in some organs?
No evidence for acromegaly or Pagets.
Demay, et al., PMID 38828931
The patient is actively breastfeeding.
Many patients are interested in romosozumab for "maximizing bone gain" and preventing future fractures. Some have had anabolic therapy with teriparati...
The patient has very low urinary calcium despite calcium supplements, vitamin D used to be low now normal. Continues to have elevated PTH with normal ...
After replacing Vitamin D, what will be your first treatment of choice? Labs including ALP and calcium levels are normal. T scores are -3 or above. Th...
If so, when? Does surgery need to be timed with last dose of Prolia injection?
A male patient in his 30s with two lumbar compression fractures (non-traumatic) and a Z-score of -2.6 in the spine, Z-score -0.5 in hips. History of 3...
I’ve seen several such patients who have no secondary causes for bone loss, on adequate calcium/vitamin D, and compliant with denosumab who do n...
Should this patient population be treated differently?
At our institution, we have started using EPIC to screen many patients for osteoporosis and ou...
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Papers discussed in this category
The lancet. Diabetes & endocrinology, 2019 Aug 22
JBMR plus, 2021 Aug 30
World journal of surgery, 2004 Apr 19
Arteriosclerosis, thrombosis, and vascular biology, 2019-07
Clinical journal of the American Society of Nephrology : CJASN, 2017-08-07
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2018-10-05
Joint bone spine, 2021 May 19
Genes, 2022 Oct 17
JAMA, 2007-01-24
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2017-07
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2019 Dec 01
JAMA network open, 2022 Oct 03
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2022 Oct 17
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2020 Mar 16
Current osteoporosis reports, 2021 Feb 01
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2023 Jul 01
The New England journal of medicine, 1980-02-21
The New England journal of medicine, 2018 Sep 13
Frontiers in endocrinology, 2023 Dec 04