Questions discussed in this category
Is a biopsy or EMG helpful in confirming the etiology? What is the best treatment for sarcoid neuropathy?
Given poor pulmonary outcomes in people with anti-PL12 antibodies, would you recommend more aggressive therapy? The patient was diagnosed with onset o...
Would you use with DMARDs/biologics or monitor?
Do you use biomarkers or PET scanning to stratify patients who may benefit most from therapy?
This question is part of a collaboration with RheumMadness and is in reference to Pathogenic ANCA (RAVE Trial).
Do you obtain serial cardiac PET scans?
Patient became acutely flushed, developed severe and prolonged hypotension with brief loss of consciousness, dizziness, nausea, dry heaves and headach...
Do you typically push for myocardial biopsy in this case?
While classically described as seen in seropositive patients, have they been reported in seronegative RA?
Patients on baseline mycophenolate and azathioprine were excluded from the INBUILD trial however many patients with CTD-ILD will be on some form of im...
Do you base the decision on FEV1, 6MWD or symptoms at initial evaluation, or progression over time?
When adding nintedanib what sort of treatment course do you counsel the patient on? Do you plan to continue it indefinitely as long as the patient tol...
Do you prefer to start with nintedanib and then add immunosuppressive agents, or give a trial of immunosuppressive medication first, then add nintedan...
Any indications for triple therapy in the patients with subclinical ILD associated with MDA-5 dermatomyositis?
Assuming other non CTD related causes for PAH have been excluded
Would you suggest switching to a viral vector vaccine, such as J&J?
Would you discontinue Methotrexate and TNF inhibitors even if previously no side effects from these medications, and would you consider Cyclophosphami...
Would you have a different opinion based on whether it is a new therapy or an existing and previously well-tolerated therapy for the patient?
Do you use imaging (fibrosis vs. pneumonitis), PFTs, duration of prior immunosuppressive therapy?
Would you change rituximab maintenance dose or schedule?
How is your approach to treatment different than other ILD patterns such as NSIP? Does treatment response vary based on underlying CTD?
Cyclophosphamide/tacrolimus and Rituximab have been used in conjunction with steroids in case series.
Does the type of cardiac involvement impact this choice?
If so, what would be an ideal DMARD in this setting?
If you use both, how do you decide which to use for a particular patient?
The SENSCIS trial was published in 2019 on efficacy of this agent. However, it's not clear where this should be in the treatment algorithm: Monot...
Is IO related pneumonitis in the radiation field or more diffuse?
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Papers discussed in this category
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Drugs,
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