General Hospital Medicine
Questions discussed in this category
Are there situations in which you still feel comfortable giving IV iron? If not, do you consider PO iron?
For example, anticoagulation for recent, significant PE or dual antiplatelet therapy for recent MI, but requiring urgent procedures such as biopsy of ...
McCreary et al., PMID 37310038
Is there an absolute cutoff for AST/ALT that you use where the risks outweigh the potential harm reduction benefits of using the medication? &nbs...
Do you prescribe it universally or based on specific risk factors?
Especially if Watchman is an option, which would still require temporary anticoagulation post-procedure.
Is there an advantage between saline and LR?
Young adult male previously without bleeding diathesis and no family history. Platelet count, PT, and PTT are normal. Also normal factor 8, 9, 12, 7, ...
Do you still find urinalysis helpful in this situation, or do you rely on more specific culture data, imaging studies, etc.?
What factors might drive decisions for different SSRIs and/or doses?
Do you involve additional specialists, such as ENT, to further evaluate? Is there a particular algorithm followed by your institution, or is it just d...
Given the unprovoked nature, do you favor indefinite anticoagulation? Would a presentation with bilateral distal DVTs or other concerns for thrombophi...
For example, do you consider "cautious" IV fluids or otherwise consider early vasopressors?
Rahman et al., PMID 38224592
For example, do you target K >4 and Mg >2?
If it's reasonable to stop anticoagulation, how frequently should patients be monitored for AFib/atrial arrhythmia recurrence?
In what patient populations would you consider using disulfiram (Antabuse) instead of, or in addition to, acamprosate or naltrexone? In your experienc...
Klementova et al., PMID 40795115
Rogers & Rice, PMID 38018162
How do you critically assess the evidence base for functional medicine approaches? How do you respond when patients specifically request functional me...
Assume QTc is not prolonged, electrolytes are reasonably normal, and the patient is not already on heavy psychotropic polypharmacy.
If they have been on IV heparin for 3 days, for example, would you subtract those days from the recommended loading dose time?
Would you initiate both medications at the same time?
For example, what do you do when someone requests aggressive, life-prolonging treatments but then is not receptive to elements of day-to-day care in t...
When do you have consider sending them as part of your initial workup?
Do you prefer anticoagulation? Is there a role for aspirin? How strongly do you recommend line removal?
In particular, how do you reconcile situations where lung POCUS findings contradict other components of volume assessment (e.g. JVD, peripheral edema,...
Tabaja et al., PMID 38635420
Do you commonly use prognostic tools such as PRESS to aid in your decision?
Are there situations in which you would continue the possible offending agent with close monitoring?
Do you find them more helpful as predictors of perioperative risk or as a baseline to detect post-operative adverse cardiac events?
For example, do you find trending WBC, procalcitonin, CRP, etc., more or less helpful?
What situations prompt you to prescribe dexamethasone to complete a 10-day course at discharge?
If these patients were already prescribed non-selective beta blockers outpatient, do you recommend withholding these medications in the acute phase?&n...
What additional assessments and considerations would you suggest to comprehensively evaluate the underlying cause of the rhythm disturbance and ensure...
Mahé et al., PMID 40162636
Would you be comfortable with the use of DOACs?
Do you extend the course of fidaxomicin past initial 10 days to at least 3-7 days after completion of antibiotics?
Do you use the traditional strict limit of 1.5 L, or do you consider removing more volume if a patient appears to tolerate it?
For example, would you consider alternatives to paracentesis (Denver shunt placement, CART therapy, or permanent tunneled catheters) that might better...
Primary care providers often check iron studies during workup for fatigue, even if anemia is not present.
What non-pharmacological interventions do you recommend? Do you routinely prescribe prophylactic laxatives to patients initiating opioids? How do you ...
Such as a patient who cannot tolerate oral iron and has had a anaphylaxis to intravenous iron
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Papers discussed in this category
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Journal of the American College of Cardiology, 2025 Feb 27
Kidney international, 2019-04
Kidney360, 2023 Feb 10
Frontiers in medicine, 2022 Mar 17
The international journal of cardiovascular imaging, 2021 Feb 05
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014 Jul 15
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Antimicrobial agents and chemotherapy, 2014 Feb 03
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013-06
JAMA, 2012-01-11
Mayo Clinic proceedings, 2015 Aug
Circulation, 2017 Oct 03
Heart rhythm, 2017 Oct 30
The New England journal of medicine, 2025 Aug 29
N Engl J Med, 2021 Aug 27
JACC. Heart failure, 2022 Mar
The New England journal of medicine, 2023 Aug 25
The New England journal of medicine, 2024 Nov 16
Journal of the American College of Cardiology, 2023 Apr 19
Annals of emergency medicine, 2006-01
Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2019-01
Neurology. Clinical practice, 2020 Aug
Cureus, 2020 Nov 18
European journal of endocrinology, 2023 Aug 02
Journal of the American College of Radiology : JACR, 2024 Jun
AJR. American journal of roentgenology, 2010-02
The New England journal of medicine, 2023 Aug 17
Thorax, 2009 Oct
Journal of cardiac failure, 2021 Oct
JAMA, 1989 Feb 10
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018 Aug 01
JACC. Heart failure, 2024 Aug 31
The New England journal of medicine, 2025 Mar 29
Circulation, 2021 Oct 04
Circulation, 2024 Sep 24
The New England journal of medicine, 2021 Mar 04
The Journal of clinical endocrinology and metabolism, 2022 Dec 17
J Bone Miner Res, 2024 Aug 21
J Clin Endocrinol Metab, 2023 Oct 18
JHEP reports : innovation in hepatology, 2024 Apr 10
The American journal of psychiatry, 2016-05-01
The American journal of psychiatry, 2016-05-01
JAMA, 2014 Feb 19
Frontiers in aging neuroscience, 2023 Mar 03
Journal of Alzheimer's disease : JAD, 2020
Journal of the American Geriatrics Society, 2025 Apr 28
Diabetes research and clinical practice, 2021 Mar 08
Journal of diabetes, 2025 Jun
Blood advances, 2018-11-27
Blood Adv,
Lancet Oncol, 2015 Feb 19
European urology, 2022 Apr 22
Arteriosclerosis, thrombosis, and vascular biology, 2020 Sep 03
The Lancet. Oncology, 2010 Apr 13
Frontiers in cardiovascular medicine, 2022 Mar 16
Cancer, 2015 Jul 06
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2024 Jun 12
American family physician, 2022 Sep
Journal of the American College of Cardiology, 2024 Jun 25
Am J Respir Crit Care Med, 2019 Sep 1
Chest, 2023 Oct 07
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024 Mar 05
JAMA, 2025 Sep 15
Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2024 Oct 29
The Journal of antimicrobial chemotherapy, 2025 Aug 07
JAMA, 2020 Nov 03
BMJ (Clinical research ed.), 2022 Nov 23
Circulation, 2023 Nov 30
JAMA, 2025 Oct 14
PloS one, 2021 Jun 24
The New England journal of medicine, 1985-04-04
The Laryngoscope, 2017-06
Arthritis & rheumatology (Hoboken, N.J.), 2020 Nov 29
Muscle & nerve, 2012-08
Muscle Nerve, 2024 Mar
Muscle & nerve, 2018 Sep 11
Neurology, 2014 Aug 27
The Cochrane database of systematic reviews, 2014-03-21
Translational psychiatry, 2022 Apr 01
Journal of sleep research, 2020 Dec 02
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2016 Jan 27
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022 Dec 01
CNS drugs, 2024 Aug 09
Pract Neurol, 2022 Sep 26
PloS one, 2020 Apr 24
Magnetic resonance imaging clinics of North America, 2009 May
Antibiotics (Basel, Switzerland), 2024 Aug 16