Testicular Cancer   

Questions discussed in this category



What is your approach to a patient who underwent surgery for what was thought to be a thymoma, but ended up being a pure seminoma? No disease elsewher...

Would you think differently about chemotherapy based on %teratoma or size of lymph nodes vs number of lymph nodes (eg. multiple small LN vs single 2-5...

Does patient age effect your approach? Would you consider RPLND for any patients in light of the phase II SEMS trial presented at the 2021 ASCO GU Ca...

Are there any chemotherapy regimens that can be used in elderly patients with poor PS who are not candidate for BEP?

In reviewing the data, LDH does not upstage to intermediate risk but those patients tend to do worse. Would one treat this patient as intermediate ri...

Would you radiate? Surgery? Chemo? Follow with short interval scans? How would size of adenopathy (e.g. <2cm vs larger) and time of recurrence (wi...

If no testicular mass on exam or ultrasound - is there a role for orchiectomy? What chemotherapy regimen would you use and how many cycles?

An ASCO 2020 poster from the German Testicular Cancer Study Group found that 37% of CSIS seminoma and nonseminoma were miscatagorized resulting in ina...

Should treatment be based on current histology (rhabdomyosarcoma) or origin (germ cell)?

There are conflicting reports of increased incidence of bleomycin-induced lung toxicity with G-CSF.

i.e. gross disease on scans that is too diffuse to be removed completely and/or decreasing but not normal markers Do you pursue close surveillance, s...

How do you assess risk of tumor lysis syndrome, and is hydration sufficient or should hypouricemic agents be used as well?

In a patient s/p orchiectomy and with pelvic lymphadenopathy, would you consider lymph node biopsy to confirm involvement by non-seminomatous germ cel...

When are you concerned for a false positive? FDA guidelines include a suggestion to try another assay in case heterophile antibodies are causing a fal...

Would a history of prior vasectomy in a stage IIA seminoma be an indication to include the inguinal nodes in the RT treatment field?

Is there any advantage to primary RT as opposed to just orchiectomy? Additionally, in order to confirm Tis, a biopsy is required, which is typica...

The Chung validation study did not find that size > 4cm or rete testis invasion are risk factors for relapse and the current NCCN guideline discour...


Papers discussed in this category


Indian J Urol,

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-12-20

Annals of oncology : official journal of the European Society for Medical Oncology, 2010-04

J. Clin. Oncol.,

Chest, 1997-03

J. Clin. Oncol.,

Clin Genitourin Cancer, 2017 Sep 04

Eur. Urol., 2020 Jan 01

Journal of the National Cancer Institute, 2005-09-21

Eur. J. Cancer,

Br. J. Cancer, 2007 Jan 30

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2001-03-15

Clin Nutr, 2015 Aug 28

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-07-10

The New England journal of medicine, 1980-11-13

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2016-02-01

Cancer, 2020 Mar 15

J Clin Oncol, 2021 Apr 06

Ann Oncol, 2007 Mar 09

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1996-04

Andrology, 2014 Oct 01